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Isoview/ipamadol caused thyrotoxicosis?

by modine, Jul 05, 2009 09:55PM
This blood work was from the emergency room when my heart started skipping beats, they wouldn't do a free T3 there. I have other blood work that was pulled at the GP's office, but I don't have those results, or the results from the thyroid ultrasound yet. I have been self treating with a juice blend, beets, carrots, radish, lettuce, pineapple, and kelp, I feel better, the swelling is going down and my swallow is better too, but then I read iodine is the wrong thing to take in some instances. I read that reactions to CT dye can cause throtoxicosis in some cases...
"Dehydration and/or the risk of renal failure may be exacerbated in geriatric patients, especially those with polyuria, oliguria, autoimmune diseases, diabetes, or pre-existing dehydration from previous iopamidol. Adequate hydration is recommended before and following administration of iopamidol. The elderly may be more sensitive to the effects of iopamidol on thyroid function. Iodine-induced thyrotoxicosis may occur 4 to 12 weeks following contrast radiography. Thyroid function monitoring may be needed in geriatric patients."
I guess I'm not quite a geriatric, but I do have fibromyalgia. NO ONE told me to hydrate myself before or after the CT and I ended up in the emergency room the day after with heart palpitations, a UT infection and painful burning feet. Months later my feet still hurt and burn at night and now my thyroid is acting up.
Free T4 1.25 (0.74-1.83)ng/dL
TSH 0.470 (0.46-4.70) uIU/mL     ----how can a range this wide be considered "normal"
amylase 57  (30-110)mg/dL
glucose 78   (70-100)  "
sodium 141  (135-145)MEQ/L
potassium 4.8  (3.5-5.5)   "
chloride 103     (98-107)   "
co2 29             (23-31)    "
anion gap 8    (7-16)        "
bun 15               (5-25)        MG/DL
creatinine 0.66   (0.50-1.00)     "
calcium 9.8          (8.7-10.2)    "
bilirubin total 0.5       (0-1.0)     "
bilirubin direct 0.0      (0-0.4)    "
total protein 8.0      (6.3-8.2)  GM/DL
albumin 5.2             (3.5-5.0)     "
ast 27                      (8-39)     U/L
alt 25                      (9-52)        "
alk phosphatase 82   (50-136)   "
ggtp 17                      (8-78)     "
egfr >60                       >60
lipase 112                  32-300   "
Thank you for your help and any suggestions.
Member Comments (1)

by Smilerdeb, Jul 06, 2009 12:49AM
I answered another posting like this in regards to contrast dye.
I would suggest that anyone who has to have contrast dye...print this out as the info is invaluable.

There are 2 types of contrast that they use for CT, MRI, X-Ray, RAIU.
************************************************************************************************************

MRIs and CT scans do not use radioactive dyes, but a non-radioactive
contrast media, usually gadolinium. (Gadolinium has no iodine, so it
causes few allergies.)
While SestaMIBI, used for stress testing, thyroid scans and mammograms,  is radioactive.

To have a computed tomography scan (CT scan) done, you may need to have an injection of "contrast" or "dye." This liquid is visible on X-ray pictures or CT scans, so once it is injected it will cause your blood vessels to be visible to the radiologists. This makes your anatomy very clear. "Contrast" also can highlight areas with inflammation because blood flows more generously to inflamed areas.
The reason that contrast dye is visible on X-rays is because it contains highly concentrated iodine.

Some reactions to contrast dye are allergic, but the trigger for the allergy has not been precisely identified. Doctors have noticed that older dye preparations that have a high concentration of iodine are more likely to trigger a reaction. Contrast dye has been adjusted in a variety of ways in order to make it less likely to cause a reaction.
Iodine has not been removed from contrast dye, but the dye is now prepared so that the iodine is chemically "hidden" from your immune system. Your immune system does not detect the iodine easily since each iodine particle is packaged inside a complex salt.
The newer dye is called "non-ionic" or "low-osmolar" contrast.

You can ask your doctor to use one of the newer dyes, which while are more expensive, are far less allergenic.
You may also be prescribed an antihistamine of cortisone before the procedure to lessen the chance of an allergic reaction.


I am allergic to the Iodine based dye Pertechium so for my thyroid tests they used the newer one and I had no problems.
I had the same reaction as you did with previous tracers and felt like I was going to die!

Please ask your Doc for the 'low-osmolar' contrast.

Hope that helps.
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