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Plz help

Symptoms- constant fatigue, weight loss, inability to concentrate, excess sleep.

My thyroid results( 3 tests last one is recent)

1. TSH below .01, Vit d below 20 nmol/l

2. tsh 1.57( mu/L), free t3 4.2( pmol/L), free t4 13.8( pmol/L)

3. Tsh 2.36, vitd 130 nmol/l.

Should i be worried about thyroid problems as doctors said its all normal.
They ran several tests but couldnt find the reason for my problems. I never took any prescribed medicines but took vitd 10k iu daily. Thanks

Jain
11 Responses
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649848 tn?1534633700
COMMUNITY LEADER
Sorry I hadn't seen a couple of your posts... Your thyroid hormone levels are still off a bit... Your FT4 is at 60% of its range, just over the mid point, while your FT3 is only at 40%.  Most of us feel best with FT3 in the upper half to upper third of its range.  Ft3 should be higher in its range than FT4.  Your TSH looks good

I've never seen cholesterol measured in %... yours is over the recommended level of 200, though.  High cholesterol is a symptom of hypothyroidism.

I agree that you should cut back on the vitamin D.  Your B-12, on the other hand could stand to be higher in the range.  I'd suggest supplementing with a Methyl B-12 sublingual or liquid.

Lipase is an enzyme that helps break down fats.

"The blood test for lipase is most often used, along with an amylase test, to help diagnose and monitor acute pancreatitis. It may also be used to diagnose and monitor chronic pancreatitis and other disorders that involve the pancreas but is not as useful of a test for these conditions because lipase levels remain elevated for longer periods and may not reveal clinical progress.

Lipase testing is also occasionally used in the diagnosis and follow-up of cystic fibrosis, celiac disease, and Crohn disease."

I'd have to research the Lipoprotein, Apolipoprotein and chloride to see what those levels might indicate.
Helpful - 0
Avatar universal

My vitamin d is now too much at 120ng/ml. I am gonna cut it down.
Ferritin  138.5 ng/ml   reg range ( 22-322 ng/ml)

b12 is 568 pg/ml     ref range ( 211-911 pg/ml)

Strangely my total cholestrol is  292 mg%  ref range ( 125-200)
LDL cholestrol direct  136 mg%    Ref range ( 85 - 130 mg%)
I am super skinny

Some other out of range results

Lipoprotein    45.4mg/dl   Ref range ( 1.20)

Apolipoprotein     96mg/dl     ref ( 110-205)

Crp    2.12      ref( 1-3 average risk, >3 high risk)

Chloride  106.7  mmol/l      ref ( 98-106)

Lipase   80.1 u/l                ref( 5.6-51.3 u/i)
Thanks
Helpful - 0
Avatar universal
My results are here now

Total T3  82 ng/dl   ref range (60-100)
Total t4   9.8 ug/dl   ref range ( 4.5-12)
Tsh          1.86uIu/ml         range  ( 0.3- 5.5)
Free T3     2.7 pg/ml     range ( 1.7- 4.2)
Free T4     1.38 ng/dl    range  ( 0.7 - 1.8)
Anti mircosomal Antibody     18 Iu/ml    Negative <34

ANTI THYROGLOBULIN ANTIBODY (ATG)   24.74  iu/ml   Negative: <115

Aree these results ok. Thanks
Helpful - 0
Avatar universal
I will be going next week. My ferritin levls were 244 ng/ml in Nov test. Now the latest one in Jan shows 122 ng/ml.  Ref range ( 30 - 500)

It says active b12 on the report.

I was also taking tyrosine but it stopped working after around 7 weeks. It only gives me boost for one hour now.
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
Yes, those are the antibody tests.  Be sure to get Free T3 and Free T4 again, as well, since you had the one set that were low in the ranges.

Also get your vitamin B-12 tested again.  I don't trust the test you had done, because of the odd range information.  Also do vitamin D again to make sure your levels are coming up and it's also a good idea to do ferritin to check iron stores.
Helpful - 0
Avatar universal
Thanks, I am going overseas to my home country where I dont have to take doctors referral for tests.

ANTI THYROID ANTIBODIES PANEL*Antithyroglobulin Antibody *AntithyroidPeroxidase Antibody

Method Chemiluminescent Immunoassay

Are these tests and method ok.

Any other test that can be helpful?
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
Your lab is using a very odd range for vitamin B-12.  A typical lower limit in pmol/l is 145.  Your lab's entire range is below that... something seems off there.

Yes, you can still have a thyroid problem even if you don't have antibodies, but get those anyway, because if you have them, they're confirmation of a thyroid disorder and can often get you treatment sooner, rather than later.  Also ask for a thyroid ultrasound, which can determine if you have nodules on your thyroid.  Typically, nodules are nothing to worry about, but they can produce hormones independently of the thyroid, so it's also good to know if you have those.  

Typically, the symptoms of Hashimoto's are those of hypothyroidism and you don't have to have all or even most of them to have the disease.  Many of us have it for years and don't even know it.

Your doctors aren't doing all the testing they could be doing to find out why your levels are fluctuating like they are!!  Don't let them just throw up their hands and say "I don't know" - that's not going to help you.
Helpful - 0
Avatar universal
Thanks, first test was done around 3 months back, secon test 1.5 months ago and the latest was 2 weeks back.
I am now taking 15k iu of d, will increase to 20k iu. I checked the symptoms of hashimoto's disease  I don't have most of them.
My b12 is 90 pmol/l    ref range ( 23-100).

Is it possible that even if i dont have any antibodies I may stiil be suffering from thyroid problem. It is so confusing that lab results are not up to date,

my doctors are not sure why my levels were .01 and now normal. one thing more My liver tests were also abnormal the first time ALP 200, billirubin 28, ggt 80, ast 300, alt 800. After a couple of tests they came down to normal levels.
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
How far apart were these tests taken?  The first TSH indicates hyperthyroidism, but without any other tests (Free T3 and Free T4), we can't tell what might have been going on, at the time.

In the second test, the FT3 and FT4 are very low in the ranges, indicating hypothyroidism.

In the third test, the TSH appears to be rising toward the hypothyroid range (your lab is using a very old range - "new" range recommended 12 yrs ago is 0.3-3.0), but with no FT3 and FT4, we can't tell if those levels have dropped further into hypothyroidism as well.

Your vitamin D is still too low at 52 ng/ml; it needs to be closer to 70.

You should ask your doctor for thyroid antibody tests to determine if you have Hashimoto's Thyroiditis.  The tests you need are Thyroid Peroxidase Antibodies (TPOab) and Thyroglobulin Antibodies (TgAb).  Hashimoto's is often characterized by swings from hyper to hypo, with periods of normal before finally settling into permanent hypo.

Your symptoms are consistent with either hypo or hyper, except the weight loss, which is, typically, associated with hyper, but some who are hypo also lose weight.  Your labs, however, except the first one, indicate hypo..  The problem is that TSH, by itself, is pretty much useless.  You need the Free T3 and Free T4, which are the actual thyroid hormones, every time, to give a clear picture of what's going on.

Low vitamin D can cause some hypo like symptoms, plus vitamin D is necessary for the metabolism of thyroid hormones.

Because of the fatigue and excessive sleep, I'd recommend that you have Vitamin B-12 levels tested.  Vitamin B-12 deficiency can cause the most horrible fatigue/tiredness imaginable, as well as inability to concentrate or think clearly.  

If it's been more than a couple months since you  had the latest TSH test done, I'd recommend that you have another set of thyroid tests and insist that your doctor order Free T3 and Free T4 every time s/he orders a TSH test.  Also ask for the antibody tests mentioned above to confirm/rule out Hashimoto's.  And while you're at it, a thyroid ultrasound would also be a good thing to determine whether or not you have nodules or unusual characteristics on your thyroid.  This can also help diagnose Hashimoto's.
Helpful - 0
Avatar universal

Thanks, Free t4 ( 11.0 - 21.0), Free T3 ( 3.2 - 6.4), Tsh ( .5 - 5.0)
Helpful - 0
Avatar universal
Can you include referance range with lab results, every lab is different.  

Helpful - 0
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