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SU thrips, omeprezole

I have hashimoto and have been on synthriod 1.12 mcg for years. Lately I have had some breathing issues and dr put me on opeprizole 20 mg at night. Recently they added AM dose too. All of a sudden I have gained 5 lbs. Can this be from combination as I take then together?
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Avatar universal
Check this listing of typical hypo symptoms.  You'll find shortness of breath.

http://endocrine-system.emedtv.com/hypothyroidism/hypothyroidism-symptoms-and-signs.html

Since you had trouble with the other link, I've just copied it below.

For Physicians of
Patients Taking
Thyroid Hormones

I have prescribed thyroid hormones for your patient because his/her symptoms, physical signs, and/or blood tests suggested that he/she had inadequate levels for optimal quality of life and long- term health. If there were clear improvements, I maintained the thyroid supplementation. Mild-to- moderate thyroid insufficiency is common and an unrecognized cause of depression, fatigue, weight gain, high cholesterol, cold intolerance, atherosclerosis, and fibromyalgia. Thyroid supplementation to produce higher FT3 and FT4 levels within the reference ranges can improve mood, energy, and alertness; help with weight control, and lower cholesterol levels.

Your patient’s TSH may be low or undetectable, even though their free T3 and free T4 are within the reference ranges. Why? We are taught that the TSH always perfectly reflects a person’s thyroid hormone status, supplemented or unsupplemented. In fact, we have abundant evidence and every reason to believe that the hypothalamic-pituitary axis is NOT always perfect. In clinical studies, the TSH was found not useful for determining T4 dose requirement.i The diagnosis of thyroid insufficiency, and the determination of replacement dosing, must be based upon the patient’s symptoms first, and on the free T4 and free T3 levels second. The TSH test helps only to determine the cause. Even here, “normal” may not be good enough. The labs’ reference ranges for free T4 and free T3 are not optimal ranges; but only 95%-inclusive statistical population ranges. The lower limits are below those seen in studies of healthy adults. They define only 2.5% of the population as “low”, but hypothyroidism is more prevalent than that.  

T4-only therapy (Synthroid, Levoxyl), to merely “normalize” the TSH is typically inadequate as the H-P axis is often under-active to begin with, is more sensitive to T4, and is over-suppressed by the once-daily oral thyroid hormone peaks. TSH-normalizing T4 therapy often leaves both FT4 and FT3 levels relatively low, and the patient symptomatic. Recognizing this, NACB guidelines call for dosing T4 to keep the TSH near the bottom of its RR (<1) and the FT4 in the upper third of its RR; but even this may not be sufficient. The ultimate criterion for dose adjustment must always be the clinical response. I have prescribed natural dessicated thyroid for your patient (Armour or Nature-Throid). These contain T4 and T3 (40mcg and 9mcg respectively per 60mg). They are more effective than T4 therapy for most patients. Since they provide more T3 than the thyroid gland produces, the well-replaced patient’s free T4 will be around the middle of its range or lower, and the FT3 will be high-“normal” or slightly high before the AM dose.

Excessive thyroid dosing causes many negative symptoms, and overdosed patients do not feel well. I suggest lowering the dose in any patient who has developed insomnia, shakiness, irritability, palpitations, overheating, excessive sweating, etc. The most serious problem that can occur is atrial fibrillation. It can occur in susceptible patients with any increase in their thyroid levels, and is more likely with higher doses. It should not recur if the dose is kept lower than their threshold. Thyroid hormone does not cause bone loss, it simply increases metabolic rate and therefore the rate of the current bone formation or loss. Most older people are losing bone due to their combined sex steroid, DHEA, Vitamin D, and growth hormone deficiencies. The solution is not life-long hypothyroidism or bisphosphonates; one should correct the hormone deficiencies.  
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Avatar universal
Can't get to that website. Can you please check address. Except to recent weight gain and some shortness of breath  there are no other symptoms. Shortness of breath they r checking for esophagus spasms.

Could t3 or t4 have anything to do with shortness of breath?
If you could Resend the website for that article that would be great
Helpful - 0
Avatar universal
Yes you should request testing for Free T3 and Free T4, not Total T3 and Total T4, along wtih TSH that they always test.  The Free portion of thyroid hormone is the only part that is biologically active.  If the doctor resists then you should insist on it and don't take no for answer.  FT3 largely regulates metabolism and many other body functions.  Scientific studies have shown that FT3 correlated best with hypo symptoms, while FT4 and TSH correlated very poorly.  

You should also be aware that FT3 and FT4 results in the lower end of the reference ranges are frequently associated with being hypo.  The reference ranges are far too broad.  Many members report that hypo symptom for them required that FT3 was adjusted into the upper part of the range and FT4 adjusted to at least midpoint of its range.  

A good thyroid doctor will treat a hypo patient clinically, by testing and adjusting FT3 and FT4 as necessary to relieve symptoms.  Symptom relief should be all important, not just test results.  Test results are valuable mainly as indicators during diagnosis, and then afterward to track FT3 and FT4 levels as meds are revised to relieve symptoms.

In preparation for getting the testing suggested and the treatment needed, I think you will get some good info from this link.  The letter was written by a good thyroid doctor for patients that he consults with from a distance.  The letter is sent to the PCP of the patient to help guide treatment.

http://hormonerestoration.com/files/ThyroidPMD.pdf
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Avatar universal
Thanks. I don't have those right now.  When tested for t4 and tsh 5 months ago - dr said they were fine. I don't go to endocrinologist- just primary. I have an order for new test. I can go a month early but she didn't request t3. Only t4   Should I ask her to change it?
Helpful - 0
Avatar universal
No.  More likely is that your levels of the biologically active thyroid hormones, Free T3 and Free T4 are lower than you need.  If you will please post your thyroid test results and reference ranges shown on the lab report, members can assess the adequacy of testing and medication.  
Helpful - 0
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