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Synthroid or try Tirosint

Hello, I am new to this site. I had a TT June of this year. I went through IRA in July. Started .100mg  Levothyroxine on 8/8 for 2 weeks and Dr. tested me and said I was off the charts, so started me on Synthroid .125mg  
Started with the new endo Dr. in Sept.and she wanted to keep me on Synthroid .125mg but added 5mcg of Liohyronine right away. I got so upset and called the Dr. and got in to see her after I complained of side effects 10/23. She ran a couple of blood tests right away on 10/10 Results are:
TSH  0.102 range 0.350 - 5.000
FT3  3.0 range 2.2 - 4.0
FT4 Reflex  1.2 0.8 - 1.5
She likes these results and wants to test me in Dec. with no changes.
My complaints, I think are side effects from Synthroid and I told them all to her on the visit, and I was very upset.
Here's what I was told. Excessive hair loss (about 1/2 my hair has fallen out) She said to try Biotin and a hair loss shampoo and that with winter coming everyone has hair loss. I have been trying both of these with no help. This is horrible and is really bothering me.
What I call cold sweats. My skin is cold, but I am sweating. She said it could be menopause, but I didn't feel this way before.
I wake up with a headache every morning. She say's it could be weather. But this only started when I started these meds. I can't take asprin because I've had back issues and getting injections.
Restless sleeping. She said to take Melatonine which I started and I have had no change in my sleeping.
Charlie horses that make me jump out of bed, almost every night. So she told me to take Magnesium. So I have been taking it. My lab test 7/1 was 1.9 range 1.6 - 2.4
Feet cramps, so she wants me to drink 4oz of tonic water ever day.
Is there help for me?
Thank you.
32 Responses
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649848 tn?1534633700
COMMUNITY LEADER
Thyroid meds should always be increased in the lowest possible increments. Sometimes we have to get creative to hit "in between" dosages.  I've alternated dosages, split pills, etc to get what I needed. Jumping from 112 mcg to 137 is likely too much, and you would have jumped right over 125 mcg.  

"Adverse reaction" to thyroid medication, doesn't always mean hyper; it can be a reaction to fillers/binders in the med, but of course, the RN from Synthroid isn't going to tell you that, because you might stop taking their med.

It's not the least unusual for symptoms to worsen or for new ones to appear when one is making changes to thyroid hormone dosages.

Like I said, I had the sweats and hair loss when I was very hypo; those were symptoms before I ever started on thyroid med.  I haven't been prone to headaches since I was in my early 20's.  All the rest of the symptoms you listed (dry skin, sleep disturbed, nervousness) can be those of either hyper or hypo.  Again, when I was hypo, my skin felt like alligator skin that,actually, "flaked" like dandruff.  I slept very little, taking a couple hrs or more to fall asleep then only staying asleep for a short time (an hour/two or less).  Of course, all of this made me a nervous wreck, because I had a full time job to go to every day (getting up at 3:30 am), plus other responsibilities and I didn't have what it takes to keep up.

Weight gain is a major symptom of hypo and so  many of us suffer from it, but there are also other things that can contribute, such as insulin resistance/metabolic syndrome.

Which brings me to ask -- what are your cholestero/triglyceridel levels like?
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Avatar universal
If I have symptoms of Hypo, should my Synthroid go to .112 or .137
I think the adverse reaction would be the sweats, the hair loss, headaches for sure.
The cramps I'm not sure about. Still have problem with weight, dry skin, sleep disturbed, nervousness.
Well it's all confusing.
Thanks for the help.
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Avatar universal
Thank you, I will check these out.
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Avatar universal
Barb is right on the mark.  If you want confirmation that your symptoms can be hypo related, have a look at this link.  

http://hypothyroidmom.com/300-hypothyroidism-symptoms-yes-really/

Further if you would like some supporting info, here are only two of many references to scientific studies I can provide.  If you read through these links I think you will be a lot more confident in what we have told you.

http://www.hormonerestoration.com/Thyroid.html

http://www.ncbi.nlm.nih.gov/pubmed/1366242
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649848 tn?1534633700
COMMUNITY LEADER
I agree with gimel, that the RN was looking only at the TSH.  Yes, those symptoms are those of being over medicated, but I had them all when I was very hypo, as well.  My TSH has been at < 0.01 for the past 5 years and I've never been over medicated or had hyper symptoms.  

I do agree with the RN that TSH levels should be between 0.3 and 3.0, but that's about it.  Once a person is taking a thyroid hormone replacement hormone, TSH becomes totally and completely irrelevant.  It does not correlate with symptoms, or does it cause or alleviate any symptoms.  Those in the medical field would have you believe otherwise.

Since FT3 is the active thyroid hormone that's used by the individual cells, that's the one that indicates actual thyroid hormone status.  Low levels indicate hypo.



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Avatar universal
Oh, forgot, test on 10/10 was without me taking T3. It was just me taking .125 Synthroid. That's the day she started me on T3. So you are right, I was low on T3. The test on 12/27 will be with the T3 5mcg of Liothyronine and the .112 Synthroid.
Happy Thanksgiving
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Avatar universal
The RN said the extreme hair loss, nervousness, excessive sweating, not sleeping good + more suggested to her overmedicated. She also said the TSH at .102 is too low for the recommended levels of Synthroid. The levels recommended are .3 - 3.0 When dealing with Synthroid they only watch the TSH levels.
My Dr. watches the freeT3 and freeT4 levels. But I have symptoms that the levels do not explain. There are side effects and adverse reactions from taking the thius drug. The RN from Abbott feels I am suffering from adverse reactions from the dose of Synthroid.
My Dr. is changing me from .125 to .112 and then wait to see if some of the reactions subside. Only way to find it out is to try it for 6 weeks. I will have new blood work done on 12/27 and see my Dr. 12/30
Thank you
Helpful - 0
Avatar universal
In my opinion the RN was only looking at the TSH result.  She has no idea that TSH is often suppressed when taking adequate thyroid med.  There are lots of scientific data supporting this.  A low TSH does not mean you are hyper, unless you have hyper symptoms, due to excessive levels of Free T3 and Free T4, which you did not have in the last test results.  

I also think that your Free T3 is too low in the range and is most likely the cause for your symptoms.  Why do you think you are overdosed?  
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Avatar universal
Thank you for writing. I will check into the magnesium. Did not know it would take that long to take effect.
Talked to the RN from the drug company and she said I am overdosed. She said my symptoms are adverse reactions from being overdosed. She said call your Dr. today.
So I called my Dr. today and she is willing to put me on the next dose down. She said then we'll see if symptoms are from overdosing.
Finally!!  
If I get more balanced, I may want to try Tirosint. I have heard a lower dose is better..
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Avatar universal
Please click on your name and then click on messages.  I sent a PM for you.
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263988 tn?1281954296
Forgot to add that I am on Tirosint and I love it. I'm allergic to many additives and have no problems with Tirosint.
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263988 tn?1281954296
I find that a "cocktail" of magnesium and calcium works best about one hour before bedtime. I use a brand of magnesium which enables me to take more at a time. It is called magnesium glycinate. I have atrial fibrillation and that necessitates taking anywhere from 600 to 1000 mg per day depending on the need. Magnesium glycinate allows me to take that amount with gastrointestinal symptoms, whereas magnesium citrate would not allow me to do so. It took a lot of research to find the right match. I split my dose and take 300 mg before bed.

What you need may vary.

If you're under medicated or overmedicated, no amount of a calcium/magnesium supplementation will help you sleep or your muscle cramps as those symptoms are caused by under/overmedication with thyroid meds.

A reality about magnesium which shocked me. It takes the same amount of time as the thyroid med does to reach optimum levels throughout your whole body. One year.
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649848 tn?1534633700
COMMUNITY LEADER
Sending you a PM.  Check your "inbox".

Yes I've leveled out... Sad to say it took nearly 4 years, because of doctors who wanted TSH in line... I won't go there.
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Avatar universal
Well, last night I thought I better not mess with the dose, so I took the .125 Synthroid and guess what?
Woke up with a headache this morning and jumped out of bed twice In the middle of the night with Charlie horse. Yikes! I can't win. Followed my schedule too....
Did you say your leveled out? How long did it take?
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Avatar universal
The pill is the .125 Synthroid. If I had to guess, I think 1/6 cut off.
The Endo Dr. I'm seeing has only seen me twice. She really does not know me. In her defense. First visit I really didn't complain much. Talked about the surgery, my meds, check up. She thought my .125 Synthroid should of been higher, so she added the T3. But it was a couple of weeks after that that my hair was just starting to fall out, so I called back. Nurse told me it would be just a little bit longer for dose to take effect. So I went to by my mom to support her while she had a TT. Two weeks of a lot of hair falling out. I even cut 3 inches off to take the weight off. It didn't work. So when I came back (from FL) I called again. That was enough time for her to order a blood test. Only to appease me, and stop my complaining.  That's when I went in with everything written down. She said not a lot of people check everything on the internet. lol Only other Dr. to help would be my Woman Internist.
Well not sure what to do. Blood test is around Dec 5th, See her Dec 12th
If I cut down the pill till then, not sure what she'll say after blood test.
But no headache this morning! yea! Maybe all I need are sugar pill's.
lol
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649848 tn?1534633700
COMMUNITY LEADER
Wishing often brings on that placebo effect, which isn't always all bad...lol

I wish I had a quarter for every doctor who pegged me as a hypochondriac; I also wish I could back and wave the test results in their face and make them see that they were wrong, but of course, I can't.

What's the dosage of the pill you're cutting the corner from? and how big a corner are you cutting from the pill?

Depression can be a symptom of hypothyroidism, or it can be a result, depending on how your doctor treats you.  

Have you thought of looking for another doctor?
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Avatar universal
lol, yes I know it can't work that fast but I can wish.
Well last time I went to the Dr. I had all my symptoms wrote down. I did get upset while in her office. I'm so frustrated. Anyway, after I left I thought about our conversation and I think she thinks I'm a Hypochondriac. I felt as if she was treating all my symptoms and not why I was having them. I had all of these same complaints then. But the hair loss is just getting worse.
I took a low dose, time released iron pill. I did have anemia couple of years ago. But I never lost any hair.
I am not sure if I should keep cutting off a corner of synthroid or just forget about it till Dec.
I have never been a depressed person all of my life till now. Glass has always been 1/2 full and I have been a happy person. I want to get back to feeling that way.
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649848 tn?1534633700
COMMUNITY LEADER
Just a tiny corner of a synthroid pill wouldn't have an overnight effect.  It takes a dosage change approximately 4-6 weeks to stabilize in your blood. Dry hair and hair loss are 2 more symptoms of hypothyroidism.

Strangely enough, dill pickle or olive juice, as well as the vinegar/honey/water can help with acid reflux, as well, because sometimes we don't need less acid, we actually need more.  Acid reflux is another symptom of hypo.  You might want to write all these down for your doctor.

Never heard of body odor being a symptom of hypo, but anything's possible.
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Avatar universal
lol, yes too much time...Love hoe Dr felt I wasn't hypo with my symptoms last month. Last night I took a knife and pinched off a little from my synthroid. And guess what! I actually had less cold sweats today and I might be imagining it, but I think there was less hair that came out when I combed. I only wash when I have too. But I have noticed that I have no oil build up in my hair. I used to wash my hair every 3 days, sometimes 2 if needed.
Schedule, I take the synthroid at 12:30 am
Yes, I have dill and I had some at 7:30pm while having a few foot cramps. lol
I o have some acid reflux and try to take a previcid around noon if I need one. That also interfer's with synthroid. I do try to have a little honey every day.
Had my gallbladder taken out 2 year ago along with a cyst through my liver. Guess I'm a mess. Life after 50 *****.
Talked to my mom today and she mentioned body odor! Is this a symptom ? She just had her TT Sept.
Thank you again
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649848 tn?1534633700
COMMUNITY LEADER
Yeah, if you haven't had a period in 2 yrs +, I'd say post menopause.

Any doctor who is willing can order the tests for reproductive hormones. I don't have to guess how much time you've spend on this problem; been there, done that!!  

Okay, let's think about your schedule... you take T4 med at 12:30 pm and T3 med at 8:00 am; you could take the second dose of T3 at lunch (about 12:00), with one dose of calcium at 4:00 pm and another at 8:00 pm... You can have a little leeway... it doesn't have to be "exactly" 4 hours between thyroid and calcium/magnesium.  Life isn't worth living if we have to be chained to a really strict regimen... if you can only go 2-3 hrs between thyroid med and calcium, the worst that can happen is that your thyroid med will have to be increased.

Truthfully, pickle juice (should be dill), or olive juice can help with cramps.. Another thing you might consider is 1 Tbsp apple cider vinegar, 1 tsp honey, with 4 oz water.  This can be taken anytime, because it doesn't interfere with meds.  I often do the apple cider vinegar before bed, because it, along with pickle and olive juice help with acid reflux, which is another hypo symptom...
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Avatar universal
Not sure the proper name but have not had menstrual period for 2 years 9 months. I'm 55 Post menopause?
Not sure who will help me with the reproductive hormone tests. My woman internist? Gynecologist? Guess time spent on this problem.
ok, so I have to work on schedule for calcium and T3 2 times a day. Calcium at lunch up and before 8pm and T3 am and ?
I have 2 lady friends that lmk that they swear by 1Tablespoon of pickle juice for leg cramps. lol Guess I'll give that a try instead of tonic water.
Thank you
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649848 tn?1534633700
COMMUNITY LEADER
Yeah, better to have a more absorbable calcium, rather than one that doesn't do  much.  Gummies would work.  Okay to take one in the morning, and one at night, but make sure you leave the separation between the T3 and the calcium.  Maybe calcium with lunch?

Melatonin should actually be taken a while before you go to bed.  It's suggested that TV's, computers, games, etc be turned off an hour before bed, in order to let the body know that it should prepare for sleep.  If melatonin is working right, it would help you sleep, but not make you tired during the day.

Not sure about the cold sweats; some get better when thyroid levels are stabilized, others don't if they aren't thyroid related.  What stage of menopause are you in, or have you even started?  Cold sweats can be caused by fluctuating reproductive hormones.  Have you had your levels checked?
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Avatar universal
Ok, I think I will change the tum's to a different calcium, makes sense. I can take it in the morning and at night, just have to get dose right and before 8pm. Should work good for me. Maybe gummie's! lol
The melatonin is hit or miss with me. I really don't feel any different, but Dr wants me to take it for 30 days to know if it works. But I do not feel tire during the day, so it must not be effecting me that much. I take it at 11pm so it doesn't bump into the Synthroid at 12:30am
any suggestion for cold sweats? Will it get better if my levels straightened out?
Thank you again
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649848 tn?1534633700
COMMUNITY LEADER
I'm sure you eat other foods that have potassium in them, also; just see what your level is when you get back your metabolic panel and if it's high in the range, you might want to cut back.

I don't see any reason why you couldn't take 4 of the 250 mg gummies/day; you wouldn't have to take them all at once as they could be spaced out through the day.  I don't think they'll interfere with food or med absorption.

Okay, calcium for the parathyroid issue makes sense, but the Tums really doesn't.  Tums contain calcium carbonate (chalk), which is hard to absorb.  You'd be much better off taking a calcium citrate, which is easier to absorb.  Plus, from what I've read, 1 tums only contains 500 mg calcium, or are you taking something other than the "Regular" Tums?

Calcium is actually "calming" and could help with sleep, but you have to space it 4 hrs from that levo.  You could take it at 8 PM, then the levo at 12:30 am.  Calcium is usually best taken in 2 doses, because the body can't absorb more than about 600 mg at a time.

Low thyroid levels can cause poor sleep.  Melatonin does support better sleep, for some, but it doesn't work for others.  It did help me sleep, but even 1 mg left me groggy the next day.  If you're active throughout the day and all your levels are good, you shouldn't really need a sleep aid.  

I used to take forever to fall asleep, and would wake up every hour or 2 throughout the night, but not anymore.  I track my sleep, most nights, and it, typically, takes 8-10 minutes to fall asleep and unless I have to go to the bathroom during the night, I rarely wake up till morning.

Once you have the Free T3 and Free T4 levels, you might want to discuss all these things with your doctor.
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