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TSH fluctuations and persistent tachycardia
by Khitchin, Nov 07, 2009 11:45PM
Thank you very much, doctor, for taking my question.
I am a 24-year-old female and have been experiencing many symptoms for the past couple of years, the most disconcerting of which are sleep problems, weight gain, anxiety/depression, memory loss, and profuse sweating. I recently learned that I have been in tachycardia, which would explain the sudden sweating and heat intolerance. It has been a month now since I realized that I've been above average (my resting bpm is about 100 and escalates up to 170 with casual walking). All of my ECGs and echocardiograms showed no congenital defects and 71% pumping volume. I am scheduled to see an electrocardiologist in three weeks.
I went to the ER a few weeks ago and had a TSH of 8.55 with 0.8 total T3 and 2.8 free T4. One week after my ER visit, I saw an endocrinologist who tested TSH, T3, and TPO-antibodies. TSH had dropped to 1.75 and free T3 was "normal," and TPOab was <35. We are currently awaiting test results for TSI-antibodies, celiac disease (for persistent digestive problems), and pheochromocytomas. If there is no cause for my symptoms found of these tests, my endocrinologist doesn't know what to do.
Aside from lab error, what would cause my TSH to fluctuate so widely (8.55 to 1.75) within just one week?
In terms of endocrinology, is there any other avenue to explore to explain the majority of my symptoms, but primarily the tachycardia?
Could the pituitary, hypothalamus, or HPT axis be to blame for this?
I really appreciate any thoughts you are able to provide!
I am a 24-year-old female and have been experiencing many symptoms for the past couple of years, the most disconcerting of which are sleep problems, weight gain, anxiety/depression, memory loss, and profuse sweating. I recently learned that I have been in tachycardia, which would explain the sudden sweating and heat intolerance. It has been a month now since I realized that I've been above average (my resting bpm is about 100 and escalates up to 170 with casual walking). All of my ECGs and echocardiograms showed no congenital defects and 71% pumping volume. I am scheduled to see an electrocardiologist in three weeks.
I went to the ER a few weeks ago and had a TSH of 8.55 with 0.8 total T3 and 2.8 free T4. One week after my ER visit, I saw an endocrinologist who tested TSH, T3, and TPO-antibodies. TSH had dropped to 1.75 and free T3 was "normal," and TPOab was <35. We are currently awaiting test results for TSI-antibodies, celiac disease (for persistent digestive problems), and pheochromocytomas. If there is no cause for my symptoms found of these tests, my endocrinologist doesn't know what to do.
Aside from lab error, what would cause my TSH to fluctuate so widely (8.55 to 1.75) within just one week?
In terms of endocrinology, is there any other avenue to explore to explain the majority of my symptoms, but primarily the tachycardia?
Could the pituitary, hypothalamus, or HPT axis be to blame for this?
I really appreciate any thoughts you are able to provide!
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Thank you so much for your help
http://www.medhelp.org/forums/Thyroid-Cancer--Nodules--Hyperthyroidism/show/120
Only a limited number of questions are accepted each day, so it can take a while to get lucky.