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TSH levels
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TSH levels

Ok.  Here we go.  I finally got my "stupid" endo to call me back after I told them I had contacted the ENT that first diagnosised thyroid problems.  Needless to say I've talked to him more in the last 3 days than I did at the visit.  My TSH was 7.8 (.49-4.67), T3 110 (70-204).  Hello hypohe//.  I feel miserable but anyway.  The ent suggested I start 25mcg's of Synthroid every day.  Today is day 3 of that so far no side effects.  The endo calls today and suggest that I take 12.5mcg's every day cause of the heart palpations I had back in Dec when I tried the Synthroid.  How long does it take for synthroid to get into your system?  Should I listen to endo or ent.  By the way the endo called my problem autoimmune thyroid disease.  Isn't that the same as hash's?  I'm so confused over all this stuff.  Thank God for Klonopin.  
  
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209384_tn?1231171906
Sounds like Hashi's to me.  I would pick one of them and listen to that dr and stick with them.  Whichever one you want to trust the most.  Believe you me, I know about stupid endos.  If the ENT can take care of the problem stick with him.  I'm for anyone who will call you back and actually listen.

But that's just my 2 cents worth.
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377600_tn?1225167036
A lot of doctors are now recognizing that Hash and Grave's are ends of a spectrum called autoimmune thyroid disease.  I hope you get your levels straightened out--it can take time.  Take vitamins at least four hours after the hormone because it can block its absorption.  I take my hormone early in the morning and before I eat.  I take vitamins at night.

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377600_tn?1225167036
A lot of doctors are now recognizing that Hash and Grave's are ends of a spectrum called autoimmune thyroid disease.  I hope you get your levels straightened out--it can take time.  Take vitamins at least four hours after the hormone because it can block its absorption.  I take my hormone early in the morning and before I eat.  I take vitamins at night.

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213044_tn?1236531060
Most people that have Hypothyroidism have Hashimoto's. It is the most prevalent form of "Simple" hypothyroid conditions.

The question is, what are your anti-bodies like?

Low anti-body titers= Very slow progression.

High anti-body count= faster progression.

My aunt has had hashimoto's for forty years. She doesn't even know what an Endo is. Never been to one. But she's been on meds for forty years. I would guess her dosage has gone up over the years, but I don't recall her ever having major recurring problems with her hormone levels.

My sister has had Hypothroid disease for twenty years at least. Not sure she's ever had an anti-body test, but she's never seen an Endo and she has Celiac Srue as well. (She may have seen an Endo for that one, not sure.)

I ASSUME they have very low titers of thyroid anti-bodies.

Then there are people who have TPOab titers over 1,000, over 2,000. They have a little more trouble because the disease progresses faster. They also run the risk of getting Hashimoto's Encephalopathy. Also the damage to the body from being out of whack more frequently and severely.

Other than the first sentence, none of that answers your question, though, does it?
Sorry. :)

My GUESS is it will take about a week to know if you are taking too much. It takes six weeks to come up to full strength and affect thyroid levels, so they say, which probably means a month. By two weeks you would be feeling a difference.
That is all a guess.

Which doctor you choose to listen to is up to you. You have too many cooks in the kitchen.

Before I went to my second Endo, I told my GP that he was going to be in the middle of things, and I would be uncomfortable pitting one doctor against another if I got two different opinions.

He told me not to worry about that. He would care for me and if the Endo wasn't telling me what he considered correct information, he would say so. I could do as I wished with no hard feelings on his part.

My Endo doesn't feel the same way.
But my GP gives me better advice.

Tough decision, but you'll have to make it.    
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362387_tn?1207277719
Antibodies greater than 1000
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213044_tn?1236531060
Sorry.

But then, I don't think you'd find many people on this forum with a TPOab of 50.
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168348_tn?1379360675
It takes a full 6 weeks to reach optimum levels but oftentimes within a few days you would feel good/bad side effects or effects of the med ... they say that 12.5mcgs is hardly medicinal .. that is what I was told but I understand better to go slow with your history and take baby steps.

Cheryl
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362387_tn?1207277719
I took 12.5 this am and I don't feel as good as I did.  I had taken 25 for 3 days and was starting to feel less fatigue and head swimmyness was descreasing.  I don't know what to do.  Could this be because of the synthyroid?
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362387_tn?1207277719
I'd like to have an opinion on this.  Sorry to be so persistant but I respect all your opinions and would greatly appreciate a response.  Thanks in advance.
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213044_tn?1236531060
I am not a doctor and have not stayed in a Holiday inn for ages, but I stayed in a Raddison hotel a few weeks back. :)

How soon are you going to have labs again?
When was your TSH 7.8?
How bad were the palpitations?
Intermitent and infrequent?
Constant?
Are you willing to find a new Endo if you make the one you have now mad?

Six weeks ago your TSH was 0.003, and you were told to stop taking Zoloft, correct?

Then it shot up to 6.5 in a few weeks and you were put on 50mcg. of Synthroid. Then the palpitations. So, off the Synthroid.

On 1-10-'08 your TSH was 3.72.

Now it is 7.8?

Have you started back on Zoloft?
Did anyone explain how the Zoloft is affecting your TSH?
If you go back on Zoloft is your TSH going to drop?  

Your TSH needs to get down between 0.6 and 1.4, give or take for most people. It needs to hover there for a while, not a day or two. Then you will still feel off for a few weeks because your TSH has shifted so much and so fast.

It takes time for the body to heal. At least that's what I keep hearing. My body is still trying to get to 1.0 and stay there.

I, personally, would take the 25mcg dose. 7.8 is a long way from 1.0, and I don't see how you are going to get there on 12.5mcg.

But the whole Zoloft thing confuses me.
(I dug through your journal entries.)

Before you take my advice, answer the questions and someone else will come along who knows what is what.

Don't take all the questions as being pushy.
It's hard to give good advice without knowing your history.
Best wishes.
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362387_tn?1207277719
Yeah I'm willing to find a new endo if I make this one mad.  LOL  My TSH was 7.8 last week.  They didn't tell me when to come back and do labs.  In Dec the palpations were intermittent and infrequent.  But bad enough I thought I was going to go crazy.  I have anxiety so that just made the palpations worse.  As far as the Zoloft.  No-one has said anything about the Zoloft causing problems with TSH.  Could it?  I think I read somewhere that it could.  But I can't say for sure.  Should I ask the endo and shrink?  Basically I think the Zoloft makes things worse.  But I definitely need an antidepressant.  LOL
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362387_tn?1207277719
I am answering the questions asked in the above post.  In hopes I will soon get some help and advice.  Yeah I'm willing to find a new endo if I make this one mad.  LOL  My TSH was 7.8 last week.  They didn't tell me when to come back and do labs.  In Dec the palpations were intermittent and infrequent.  But bad enough I thought I was going to go crazy.  I have anxiety so that just made the palpations worse.  As far as the Zoloft.  No-one has said anything about the Zoloft causing problems with TSH.  Could it?  I think I read somewhere that it could.  But I can't say for sure.  Should I ask the endo and shrink?  Basically I think the Zoloft makes things worse.  But I definitely need an antidepressant.  LOL
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393685_tn?1325870933
Hello Jesse,

I swear I did read anti-depressants playing some havoc on thyroid levels. I will try and check it out more since I am having an insomnia night. If I get anywhere I will write back. Maybe it was the  - take 4 hr apart thing - I do recall that for sure. I think your endo and shrink may not put the two together. Try your pharmacist. I found a real young one at the walgreens I go to and he pulls up a medication side effect and Dx discription from the Internal medicine college. I found that it really goes into a great deal of depth - more than what comes with that brochure. That is how I found out Chantix and Synthroid do not mix. and Chantix is also a "some what " of an anti depressant. But all are not alike.
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213044_tn?1236531060
I know when I had severe depression, which was after my thyroid went wacko, I begged my GP for anti-depressants. I was already on anti-anxiety meds, but they do not help with depression.

He told me he couldn't give me any, or it would mess up my treatment. He didn't explain why, though.

I just thought it was odd that your TSH was very low (0.003), and when you went off the Zoloft, your TSH went up to 6.5 very quickly.

I don't have the answers, but somebody here will.

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158939_tn?1274918797
Call me momma-Google:
Apparently T3 affects depression and the effect of antidepressants but the jury is still out on T4.

Hey - since these are scientific articles, they may help with insomnia too!  :-)

Thyroid Supplementation Enhances Antidepressant Response:  http://www.medscape.com/viewarticle/544942

Basic mechanisms of augmentation of antidepressant
effects with thyroid hormone
http://www.biopsychiatry.com/thyroid-mechanisms.htm

Thyroid Hormone Levels and Recurrence of Major Depression
http://ajp.psychiatryonline.org/cgi/content/full/157/10/1689
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