Test results can anyone Explain ?

[dwt7let]

Hi All
Please could anyone explain these results and what they mean, I have been so tired lately I am only on 75 mg's of thyroxine it has been lowered twice.
TSH is 0.77 mu/l
Thyroid Antibodies is 7 iu/ml
Thyroid Globulin is 19 iu/ml
Many Thanks
Lorraine x

[goolarra]

Unfortunately, TSH is the only test you have that indicates your thyroid status.  The other two tests indicate that you probably don't have Hashi's.  TSH is a very poor diagnostic.  Your doctor should be testing free T3 and free T4.  He should not be lowering your meds when you still have symptoms or based on TSH alone.  You might ask him to run FT3 and FT4.  If he's not cooperative, you might have to find a new doctor who knows more about thyroid.

[gimel]

To me, the main thing the results mean is that you are not being adequately tested and most likely inadequately medicated as well.  

TSH is a pituitary hormone that is affected by so many variables that it is totally inadequate as a diagnostic for thyroid status.   At best TSH is an indicator to be considered along with more important indicators such as symptoms, and also levels of the biologically active thyroid hormones, Free T3 and Free T4.  Of these FT3 is the most important because it largely regulates metabolism and many other body functions.  Scientific studies have also shown that FT3 correlated best with hypo symptoms, while TSH and FT4 correlated very poorly.

Your doctor probably reduced your meds based on the TSH test result.  That is unfortunate because TSH is frequently suppressed when taking large doses of thyroid meds.  That does not mean that you are hyper, unless you have hyper symptoms caused by excessive levels of FT3 and FT4.  For example my TSH has been about .05 for well over 25 years without ever having hyper symptoms.  In fact I continued to have lingering hypo symptoms until learning about the importance of FT3 here on the Forum.  I got mine tested and confirmed as being low in the range.  Got my meds changed from T4 to Armour, and now after some tweaking of the dosage, I feel best ever.  

What you need most is a good thyroid doctor that will treat you clinically by testing and adjusting FT3 and FT4 as necessary to relieve symptoms, without being constrained by resultant TSH levels.  Symptom relief should be all important to you, not just test results.  You can get some good insight into clinical treatment from this link.  It is a letter written by a good thyroid doctor for patients that he is consulting with from a distance.  the letter is sent to the PCP of the patient to help guide treatment.

http://hormonerestoration.com/files/ThyroidPMD.pdf