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Thyroid Antibodies
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Thyroid Antibodies

My thyroid tests came back and many doctors in my area do not know how to treat this.  Here are my recent test results:  Thyroid Peroxidase (TPO) AB >1000 (3years now), Antithyroglobulin AB 750, Thyroid Stimulating Immunoglo 195.   I want to get this under control.  I have seen three endocrynologists and they are at a loss on how to treat this other than synthroid, which I have been on for 3 years and has done nothing to improve my numbers.  Any advice would be helpful.
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213044_tn?1236531060
You cannot treat antibodies.

You can treat the thyroid for the damage the antibodies do, but there is no way to affect the antibody numbers.

Selenium, taken under a doctor's supervision, may bring the numbers down 5% to 10%, but the risk of taking too much selenium is a factor, and too much selenium will mess you up.

The antibody numbers will rise and fall regardless of what you do. They will fall if you have your thyroid removed, but they will still be present in significant numbers.
Sorry.

Your Endo should know this. If he/she doesn't know it, they are not well versed in thyroid issues. It's astounding that you have asked three different Endos about it and not gotten this information.
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Avatar_f_tn
I don't know of any other treatment other than synthroid, but that doesn't mean there's not one.  I am a "never say die kind of person", so even though you've seen three endocrinologist, doesn't mean you can't keep looking. There is lots of research material and doctors out there that focus on research and treatments of our condition. Good Luck!!!
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213044_tn?1236531060
Synthroid is a synthetic hormone to supplement the hormones your thyroid produces, or replace those hormones when the thyroid no longer produces them.

It has no affect on antibodies at all.

There is no treatment to reduce thyroid antibodies other than selenium. Selenium will help a little, but not much, and it is easy to take too much and become poisoned by it.
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Avatar_f_tn
I'm just curious are you concerned about these antibodies for fertility reasons? I'm going through a situation where the antibodies showed up during testing for infertility reasons. I went to the Endo and they diagnosed me with Hashimoto's even though my TSH was 2.5. They put me on Synthroid to get my levels down because that has shown to help some when trying to get pregnant and with miscarraige (miscarriage) risks. Otherwise my old Reproductive Endo. had put me on steriods during my last IVF cycle to try to lower the antithyroglobulin ab but I did not get prego, and a couple of weeks after the cycle my ab numbers were still high. Please let me know the reason you are questioning this, I'm just curious. Thanks and Good Luck!
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Avatar_f_tn
I test positive for antithyroglobulin antibodies and am recently pregnant.  What are my chances of miscarriage?
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Avatar_f_tn
I suggest you start a new post on this as this one is old.
Also post yr history, thyroid levels , labs, tests etc to give a clearer picture.
Good Luck :)
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