Thyroid Peroxidase and Antithyroglobulin Ab

[jdisalvo]

I had a complete thyroid lab work up this week:

Throxine Free, Direct, S      1.16 ng.dL (0.93 - 1.71)
TSH     2.0 uIU/mL (0.45 - 4.5)
Thyroid Peroxidase (TPO) Ab      78 IU/mL  (0-34)
Antithyroglobulin Ab     197 IU/mL  (0-40)
Triiodothyronine, Free      2.9 pg/mL (2.0-4.4)

Normal range is in parentheses.

What does a high Thyroid Peroxidase and Antithyroglobulin mean?

[Barb135]

It most likely means you have an autoimmune thyroid disease, such as Hashimoto's Thyroiditis.  

It's possible that your doctor may want to put you on thyroid med.  What symptoms do you have?  

[Smilerdeb]

At present your antibody levels arent that high so dont even think of getting permanant treatment and dont let the Docs/Endos tell you different.
Your antibodys are low enough at present to go into remission.
Keep your chin up.
Research all you can and then some more :)

[jdisalvo]

Vitiligo started in 2006 and is spreading on my hands, feet, elbows and knees.  Heart palpitations are getting more frequent especially at night.  Lactose intolerance started in the last 6 months. Seems like I'm nauseous most of the day.  I have also experienced short dizzy spells.  My body temp always looks 1 degree low (97.4).

I'm setting up and appointment with an endocrinologist on Monday. Seeing my doctor, dermatologist, and cardiologist in the past has been useless.  I'm with BSBSFL but I spent my own money on mymedlab.com last week to get the quick lab results above.  My doctor would never look past the TSH.

Thanks for the feedback.

[kara444]

Look into going gluten free.  Seriously.  Thyroid tissue and gluten (the protein in wheat/barley/rye) are similar, and if your body is going after gluten, it's most likely attacking your thyroid too.  Supposedly, most people with Hashi's are gluten intolerant.

It's estimated that over 50% of Americans have some some degree of gluten intolerance (most are non-celiac like myself).  Your body may attack not only your thyroid, but also your other organs, including your cerebellum.

Check out a new thyroid book by Dr. Datis Kharrazian.  It's well referenced, and very well priced on Amazon.com.  Just search on his last name, it's his first book (and the only one so far).

As a sidenote, my brother had numbers similar to yours (but with a TSH around 10), and isn't on thyroid meds.  He's been gluten free (GF) for about a month, and has had his fatigue lift significantly.

I resisted going GF for years, and am now wishing I hadn't - my TSH got up to 73 before I was diagnosed with Hashi's.  The connection between gluten and the thyroid was new to me when I read the book two months ago;  it's not mentioned in any other thyroid book I've read, and seems like relatively new info.

Good luck!