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Thyroid

Hi,
I just had blood work done to check why I have been feeling unwell and lost 15 lbs in the past month with no change to diet or exercise.  My TSH test came back as <0.01 and the T4 Free (not really sure what that is) is 2.00.  What does this mean?  Is this the cause of my fatigue, weight loss and heart racing so fast it feels like it's fluttering out of my chest sometimes?  My last doctor's appointment my resting heart rate was 126.  Any suggestions or ideas of what's going on?

Thank you for your time and responses
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Avatar universal
How long have you been on the methimazole?  Since some of your symptoms have improved, it may be that your dose needs adjusting.  I'd ask a doctor or pharmacist about the sleep aid.  One of them could probably tell you which you could take with fewest interactions.  I think your sleep will improve once you find the right dose.
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THANK YOU!!!!
Avatar universal
Endocrinologist, but that's just why we abbreviate them as "endos".  LOL

Yes, Graves' disease seems reasonable.

Methimazole is an anti-thyroid med.  It blocks your thyroid from producing excessive thyroid hormones.  The beta blocker will help with tremors and elevated heart rate.

You'll feel better soon.

How much are you taking?

Keep us posted...
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Hi there, The dosage for the Methimazole is very low at only 10 mg a day with a recheck of the blood in about 6 weeks she said.  I still feel the same for the most part except I can no longer feel my heart beating in my throat and stomach lol.  And the restless leg syndrom has lessened. (not sure if that's part of the symptoms or just coincidental).  Other than that, I am still not sleeping before 3-4 hrs at a time.  Do you know if I can take a sleep aid while on any of these other meds? Including the Propranol?  
oops, still not sleeping more than 3-4 hrs at a time
Avatar universal
Just wanted to update you on my first visit to the Endocronologist (I am not sure if I spelled that correctly).  She has diagnosed me with Graves disease.  She increased the dosage of the beta blockers, apparantly I have developed tremors.  She also prescribed a very low dose of Methimazole??  I hope this helps give some relief soon.   Thank you for your insight and sharing your amazing amount of knowledge on this topic.
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Avatar universal
I cannot wait!
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Avatar universal
Only one autoimmune is dominant at any one time.  Usually Graves' is first., which is consistent with your numbers.  You'll feel a whole lot better once you're on anti-thyroid meds.  
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Avatar universal
How in the world do you treat someone who has 2 different autoimmune diseases that characteristicly have different symptoms and different affects on the body?  This is so crazy.  I went from being an overweight but otherwise very healthy person to this train wreck that I am today.  I can't keep going on the way I feel.  I want to just crawl into a hole with a bag of ice and tell everyone to just leave me be!
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Avatar universal
So, that's a positive TSI, and it looks like you have Graves' as well as Hashi's.  140 is the point at which most people will start feeling symptoms, but people who don't have Graves' have TSI of less-than 2%.  
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Avatar universal
Sorry it was only 223 not 235...I wish there was a way to edit the post after it is sent.  
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TSI came back as 235?  Doc says normal is 140?
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Avatar universal
I do the nuclear scan tomorrow and back to the doctor to go over everything next Thursday, October 1st.  Thanks for asking.
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When do you see the doctor again?
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Ok thanks, that makes sense.  When I checked in to get the blood work done, she handed me 3 little labels to give to the lab tech doing the blood draw.  But I don't recall what was ordered.  It seems to me that the weight loss has slowed down quite a bit.  But the other symptoms are all still present.  I am looking forward to getting some answers, as I feel miserable. I would be very surprised if the doctor did not order the TSI test since, the entire time I was in his office, he kept referring to Graves Disease.
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Avatar universal
TPOab (thyroid peroxidase antibodies) and TGab (thyroglobulin antibodies) are the two markers for Hashi's.  If either is elevated, it can indicate Hashi's, but both do not have to be elevated.

TSI (thyroid stimulating immunoglobulin) is the marker for Graves'.

Since Hashi's is ultimately hypo and Graves' is hyper, it sounds like a contradiction in terms that you can have both, but you can.  One is dominant at any given time.  It might take the TSI longer to come back if they did order it.
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Avatar universal
Can you have both Hashi and Graves?  Is that possible?
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The TPOab was greater than 2000 it said.
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Avatar universal
So there should have been a 5th thyroid blood test?  I did the TSH, the T4, T3, and the Thyroperoxidase Antibody?  I thought the TSI was the same as that last test?  No?  I don't think they did anymore unless they don't give me the TSI results on line?
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Avatar universal
Let me just make sure I've got this all right:  Your TPOab result was 2000, and the reference range was less-than or equal to 5.5.  Correct?  In that case, it looks like you have Hashi's and are in a hyper phase.  When your TSI comes in, we'll know if you have Graves', too, or not.

Don't panic about the very high TPOab result.  On diagnosis, TPOab is often in the thousands.  
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The T3 was greater than 400
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Avatar universal
less than or equal to 5.5 is where this lab says it should be
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Oh crap, I am very confused or something...lab should be <=5,5
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Avatar universal
So, your TT3 is very hyper, too.  Yes, that sounds like a nuclear scan; it's called an RAIU (radioactive iodine uptake).  It actually shows your thyroid in action.  

TPOab (thyroid peroxidase antibodies) is one of the markers for Hashimoto's thyroiditis.  Hashi's is ultimately hypo, but in the early stages, it can be hyper or swing back and forth for a while.  Your result was 2000.00?  What's the reference range?  It should be something like "less-than 40".  (The less-than and greater-than signs don't work right on this site, so I find it easier to just write out the words.)
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Avatar universal
oops according to lab should be  2000.00??
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Avatar universal
Not sure what this test is, it's called the Thyroperoxidase Antibody?  According to lab should be 2000.00??  I clicked on the link about this test but it just goes over the T3 and T4 thing again?  Do you know what this is?
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Avatar universal
Sounds like they are doing a nuclear scan,  I have to go in at 8:30 and then back at 2:30 in the afternoon?  The T3 came back as >400 range should be 58-159 ng/dl according to the lab.  Still waiting on the TSI.  
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