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thyroid & fibromyalgia_ autoimmune desease?

Hi
Doctors has not diognose my desease yet. I am glad to find your site.

I have had benign thyroid nodule for several years without any disorders in T3 and T4 and TSH. But I have tested ATPO recently, the result is 29.7 IU/mL. The reference is 1-16.  
I have given a Thyroid sonography too.
Now It has several noduls two of them were calcificated, one of them was cystic and etc.

But the bigest recent problem of my body is fibromyalgia. Pain and fatigue in muscles minimally 3 months a year.

Some medical articles said that Mycoplasma fermentans infections cause autoimmune deseases and the bacterias place in neuron system and cause fibromialgya.
Is my ATPO showing thatvI  have autoimmune disease? Is it related to fibromiyalgia?
13 Responses
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649848 tn?1534633700
COMMUNITY LEADER
Ask your lab for Thyroid receptor antibodies and see if they do that... it would be the same thing as TSI.
Helpful - 0
Avatar universal
Thanks
I am going to test Tg ab and cortisol, ESR, CMP tomorrow. Here even perfect labs dont have TSI test unfortunately.
My FNA test showed No Malignancy.  Just goiter
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
Shortness of breath can be a symptom of a thyroid condition... I had it really bad when I was at my most hypo, but it can be present with hyperthyroidism as well.  I simply had to get my thyroid levels up where I needed them to be and it went away.  

Shortness of breath and a choking feeling are also symptoms of anxiety, which you obviously have, saying you're very anxious... I doubt very seriously that you have a blood clot in your lung... you simply need a doctor who will adequately test treat you.  

Were you able to get the TgAb and TSI tests I recommended?  Those would help greatly...

Anything constricting your breathing would have showed up on the sonogram.
Helpful - 0
14940421 tn?1437469122
My experience with troubles breathing occurred when my nodule was growing and constricting my breathing.  Within a couple months I had the left side of my thyroid removed.
Helpful - 0
Avatar universal
Hi
I have had a FNA on my thyroid. But after biopsy up to now I feel  shortness in my breath. I can breeth hard and I should yawn alot.
is it asthma or it is bood clot in lung. I AM VERY ANXIOUS.
I thought asthma is a symptom of fibromialgya but now I remember it came after FNA
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
No, TgAb and TSI are, both, blood tests.  You'll have to go to a lab or your doctor's office and have a blood draw in order to get those tests.
Helpful - 0
Avatar universal
Hello
Dear barb, yesterday I had FNA on my thyroid.
I want to ask you if TgAb and TSI will be shown in biopsy?
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
I will look forward to seeing the results, then I'll be able to, possibly, tell you more...
Helpful - 0
Avatar universal
Thank you very much
I am going to test these factors that you've suggested and I will tell you the results.
GOOD LUCK
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
Your T3 and T4 are Totals, which aren't as useful as Frees, but they indicate hyper rather than hypo, as they are high in the ranges, plus your TSH is low in the range...  You should ask to get a TSI test to rule out Graves Disease, since TPOab can be slightly elevated with Graves Disease..  Hyperthyroidism and hypothyroidism, often have some of the same symptoms; body aches/pain and fatigue are some of them.

Since your symptoms only appear periodically, I have to wonder if you might be in early stages of Hashimoto's, which can cycle between hyper, hypo and normal or hyper and normal.  Some people have, both, Graves and Hashimoto's.  

Studies have shown that environmental factors such as viruses and bacteria can be instrumental in causing some autoimmune diseases, though viruses have been linked to more autoimmune diseases than specific bacteria.  In some cases an illness, often caused by a virus or a bacteria, can be a trigger for someone who is predisposed, rather than a cause.

I'm not a doctor and I haven't researched the prevalence of mycoplasma bacteria, specifically, so I wouldn't rule it out as a cause of an autoimmune condition.  TPOab can be slightly elevated in several autoimmune conditions, so I'm not sure your low level would be conclusive for Hashimoto's. You really should try to get the TgAb and TSI.  
Helpful - 0
Avatar universal
Sorry I'll type it again

Idont know if they are free or not
T3 ECL 195 ng/dl ref:70-204
T4 ECL 8.7 micro g/dL  ref:4.6-12
TSH ECL 0.43 mIU/mL  ref:0.27-4.2

But I suffer from pain and fatigue not gradually and all time. Just suddenly and about 3 or 4 months a year and after experiment it disappear!

What is your opinion about Mycoplasma infection?

Thank you for your attention
Helpful - 0
Avatar universal
Has it sent?
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
Fibromyalgia is not an autoimmune disease... Elevated TPOab, typically, indicates Hashimoto's Thyroiditis even when thyroid hormone levels are within normal ranges, since symptoms of hypothyroidism are know to appear long before thyroid hormones go out of range.  It often takes years for the antibodies to do enough damage for one to become hypothyroid from Hashimoto's.  The symptoms of fibromyalgia match those of hypothyroidism and once started on thyroid hormones, they often go away.

There are 2 thyroid antibody tests, you should have had... one was the TPOab which you had; the other is Thyroglobulin Antibodies (TgAb).  Both are necessary for diagnosing Hashimoto's because some of us have one or the other; some have both.  Because your TPOab is only slightly elevated, your doctor may not diagnose Hashimoto's...

Additionally, just because your T3, T4 and TSH levels are in range, doesn't mean you don't have hypothyroidism.  Many people are hypo if their T3 and T4 are too low in the ranges.  If you'll post the actual results we can better assess your situation. Be sure to post the reference ranges, as those vary lab to lab and have to come from your own report.  Also be sure to show whether the T3 and T4 are Free T3 and Free T4 or if they are Total T3 and Total T4... they aren't the same tests and won't show the same things.

Nodules are very common with Hashimoto's, as well.
Helpful - 0
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