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thyroid peroxidase

I had a above high normal thyroid peroxidase test result. 4282.8 u/ml normal range 0.00-60.00
What does this mean?
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My TPO is even higher .. . 11,000 last time my doc told me.  I didn't realize that high of a number was so rare.  Mine was 3,000 when I was diagnosed 2 years ago.  My doc has been experimenting with dietary changes, allergy elimination, digestive support etc and giving me Armour.  All in all, I have not had to increase my Armour dosage too much since I have been diagnosed but, I struggle with a variety of crazy symtoms that I believe are due to periods of intense inflammation of my thryoid gland.
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213044 tn?1236527460
It is not good news.

TPOab attacks the tissue of the thyroid. There is a lot we could talk about on different aspects if your result was 300 or 500, but above 1,000 limits the discussion to Thyroid disease and damage to your thyroid.

Your number is not a record breaker, but very few people register over 2,000, and anything over 1,000 carries a very small risk of Hashimoto's Encephalopathy. It is a very rare condition, but with your TPOab as high as it is, you should be aware of the risk.

HE, and it is VERY RARE, causes symptoms similar to dimentia or Alzheimers, along with neuropothies and sometimes seizures. It is easily treated with some type of steroids if it develops, but it is very hard to diagnose.

This is something you should be aware of, but not worried about. There are very few reported cases.

But...your high antibody count signifies an immune system bent on attacking your thyroid until it has destroyed it.

It is probably Hashimoto's, but that is not certain until other antibody tests are run to rule out Grave's disease.

TPOab is one antibody that doctors have found a way to treat, to a small degree. Studies have shown that taking Selenium will lower the count in SOME people, by 10%-50%, sometimes more. Results are spotty, and there is no proof that it will help long term. Some people see no improvement at all.

200mcg per day is the recommended dose. Do not exceed that dosage. Be very careful you do not take 200mg instead of 200mcg, as you can poison yourself by taking too much.

It has been determined that 400mcg of Selenium is the upper limit of safe daily consumption, and we get Selenium in vitamins as well as in food we eat. So supplementing your intake with more than 200mcg per day could be risky.  
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