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Is weaning prednisone causing ALT rise?

by orphanedhawk, Sep 30, 2009 05:21PM
Anyone have any ideas of the best way to wean off prednisone?

My ALT has been yo-yoing.
I have HCV and just did a viral load test for my doc.
However I think my nurse and I have figured out the reason for my yo-yoing.

It jumped when I lowered the dosage of prednisone, just like when I stopped cellcept.  Before  it came back down but this last time, I dropped from 2mg to 1 after only 2mg weeks instead of 4 and it all shot up and I feel fuzzy. I’ve also got canker sores and I don’t know if that's connected or not.

Here’s the figures:
date     ALT     AST    prednisone
8/4       78         38    |   4mg to 3, 8/9
8/20      100       48    |  
9/2       75         43     |    3mg to 2, 9/6
9/16      110      78     |   2mg to 1, 9/21
9/29      319      242   |    eek!!!

Has anyone experienced anything like this? My tp was 4/15/09
Thanks,
OH
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