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ACTH is >2000, TSH is 33.1, creatinine is 1.39.

I'm a 42 yo male with Addision's, hypothyroidism, reneauds, who know what else. Recent blood work came back with the following concerns: ACTH is >2000, TSH is 33.1, creatinine is 1.39. Dr suggested that I double my intake of cortef and retest - ACTH went down to 1727.

MRI of pituitary for tumor was negative. Any suggestions?

Feel like I have uncontrolled Addision's Disease.
Best Answer
351246 tn?1379682132
MEDICAL PROFESSIONAL
Hi
Welcome to the MedHelp forum!
An increased ACTH can be due to Cushing's disease, Addison's disease, or ectopic ACTH-producing tumors. A cortisol challenge test is done to find out the exact cause. In Addison’s disease and in low pituitary function the cortisol is low. In Cushing’s disease, ectopic ACTH secreting tumors and in pituitary tumors the cortisol is high. Since you also have thyroid disease and Raynaud’s, please consult an endocrine specialist and a specialist dealing in autoimmune diseases. You should get antinuclear antibodies tested for various autoimmune diseases.
Hope this helps. Please let me know if there is any thing else and do keep me posted. Take care!
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Avatar universal
A related discussion, High ACTH was started.
Helpful - 0
1292759 tn?1274842988

Hello!

I'd like to help but I don't know anything about ACTH. But, please check this site and I hope this would give you even an idea.

http://www.wrongdiagnosis.com/a/acth_deficiency/intro.htm

Get well soon!
Helpful - 0
Avatar universal
Hi sir.
Im sorry i cant help you regarding ACTH. but there is a very well educated lady on the adrenal insufficiency forum called rumpled. who will be able to guide you in the right direction, regarding adrenals, and addisons.
Take care
Nicola
Helpful - 0
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