I'm a 42 yo male with Addision's, hypothyroidism, reneauds, who know what else. Recent blood work came back with the following concerns: ACTH is >2000, TSH is 33.1, creatinine is 1.39. Dr suggested that I double my intake of cortef and retest - ACTH went down to 1727.
MRI of pituitary for tumor was negative. Any suggestions?
Feel like I have uncontrolled Addision's Disease.
Welcome to the MedHelp forum!
An increased ACTH can be due to Cushing's disease, Addison's disease, or ectopic ACTH-producing tumors. A cortisol challenge test is done to find out the exact cause. In Addison’s disease and in low pituitary function the cortisol is low. In Cushing’s disease, ectopic ACTH secreting tumors and in pituitary tumors the cortisol is high. Since you also have thyroid disease and Raynaud’s, please consult an endocrine specialist and a specialist dealing in autoimmune diseases. You should get antinuclear antibodies tested for various autoimmune diseases.
Hope this helps. Please let me know if there is any thing else and do keep me posted. Take care!