CPK LEVELS HIGH, complete exhaustion

[Superandee]

I have been having periods of extreme exhaustion for 20 years. Over the years I have become almost bedridden I am so tired. The only thing constant has been a very high CPK level. Help

[Superandee]

Thank you for your post. I have had several diagnosis suggested over the many years. The one I hear most often and use for an excuse when I can no longer function is that I have Fibromayalgia. I did have a muscle biopsy when my symptoms first began at around 19 yrs old they ruled out musclular dystrophy. I turned  42 yesterday and I am trying to not give up but I feel like I am dying and I no longer have the strength or desire to fight it. I have been told that I am just depressed. I have been prescribed every anti-depressant under the sun. For years I would say I am NOT depressed I am SICK. I would refuse the anti-depressants and change doctors, for the past 5 years I knew I was depressed from being sick all the time and haven't been able to be validated. I finally started seeing a Psychiatrist in March to see if I was just crazy and the exhaustion and pain that I have was 'all in my head.'  I have been referred to and have seen a Neurologists (2), a Rheumotologist, an Obgyn specializing in difficult cases and have been to my family doctor hundreds of times. Each Doctor orders blood work and when their diagnosis  of what they thought it was going to be doesn't show up they just say they guess its the Fibro or tell me yet another kind of doctor I should see.
i would LOVE to find a doctor who could help me. I have the best insurance, which I am in jeopardy of losing very very soon because my short term disability was denied but with my weakness, exhaustion and frequent bouts of confusion i know if I go back I will be fired anyway. This is a copy of my latest blood work. If anything else comes to mind I would love to hear any theories. Also if anyone knows of a doctor who can do everything or a hospital I can check myself into please let me know.

These are the levels that came back flagged:
EOS    High (7)
BUN/CREATININE LOW  (7) Low
Sodium High (145)
Potassium Low (3.3)
Chloride High (109)
AST (sgot) high (69)
ALT (sgpt) high (98)
Creatine Kinease ALERT HIGH 1,571
Blood glucose was flagged urgent at (33) but when I went to doctor it was 202. He said he wasnt worried about the blood sugar levels that they can go between high and low.

Thanks gain to both members who posted. I really appreciated the info.

[5daughters]

In the years, have any of your physicians treated any of your symptoms, other than antidepressants, and counseling?  Any steriods, or
immunosuppressants?  
On the blood test did they do any Igg & Iga levels or C reactive protein levels?
You said an MRI was done to R/O Mascular Dystrophy, did they do an Electromyography?  
Keep looking for a physician that will treat you and not the lab results, remember lad results are subjective for specific diseases, no diagnoses can or should be made by lab work alone.  

[Superandee]

Thank you for your post. I have had several diagnosis suggested over the many years. The one I hear most often and use for an excuse when I can no longer function is that I have Fibromayalgia. I did have a muscle biopsy when my symptoms first began at around 19 yrs old they ruled out musclular dystrophy. I turned  42 yesterday and I am trying to not give up but I feel like I am dying and I no longer have the strength or desire to fight it. I have been told that I am just depressed. I have been prescribed every anti-depressant under the sun. For years I would say I am NOT depressed I am SICK. I would refuse the anti-depressants and change doctors, for the past 5 years I knew I was depressed from being sick all the time and haven't been able to be validated. I finally started seeing a Psychiatrist in March to see if I was just crazy and the exhaustion and pain that I have was 'all in my head.'  I have been referred to and have seen a Neurologists (2), a Rheumotologist, an Obgyn specializing in difficult cases and have been to my family doctor hundreds of times. Each Doctor orders blood work and when their diagnosis  of what they thought it was going to be doesn't show up they just say they guess its the Fibro or tell me yet another kind of doctor I should see.
i would LOVE to

[Red_Star]

"High CPK levels may be seen in patients who have:

Brain injury or stroke
Convulsions
Delirium tremens
Dermatomyositis or polymyositis
Electric shock
Heart attack
Inflammation of the heart muscle (myocarditis)
Lung tissue death (pulmonary infarction)
Muscular dystrophies
Myopathy

Additional conditions may give positive test results:

Hypothyroidism
Hyperthyroidism
Pericarditis following a heart attack
Rhabdomyolysis"

Medline Plus - Creatine phosphokinase test

[TheLightSeeker]

Hey Superandee. Welcome to the forum.

Please do not tell me that all these years you had no diagnosis and no proper treatment.
Polymyositis a chronic, inflammatory condition that affects multiple muscles in various parts of the body is common with people having very high CPK levels, but not exclusive.
Other possibilities include mascular dystrophy, myocarditis, rhabdomyolysis,which I think would be relatively simple to have ruled out,
if proper diagnostic work ( thorough clinical and lab testing) was performed,
from earlier on, after the onset of the symptoms.

Which makes me suspect that something important has been missed,
which at the sub-clinical level gets under the radar of "established" medical investigation, but nonetheless potent enough to cause substantial damage over time.
Hypothyroid is one of those conditions and if you search under hypothyroid type 2, you will realize that normally MDs do not test for this.

The issue is that if one has hypothyroid type 2 or low cellular thyroid function, chances are that not only the "established" serum tests may  indicate that thyroid function is good, but the patient will most  likely remain undiagnosed (or worse misdiagnosed) and suffer progressively for life.
Low thyroid function affects the cell of any organ or system of the body at the energy level, where all the various cellular functions take place, including all cell maintenance and repair.

Another such condition is an undetected low level pathogenic infection,
such as pathogenic mycoplasma, babesia, bartonella, borrelia, ehrlichia etc
Do a search for Dr. Garth Nicolson, here at medhelp for further details.
He is a part time expert doctor here and the world's leading expert in this field.
Most doctors, even most infectious disease specialists have no training in this field. Standard testing reveals very little in regards of these
infectious conditions.

Chronic stress, including hidden stress, will lead to adrenal/hormonal imbalance with the consequence of  Adrenal Fatigue Syndrome (another condition that receives no attention from doctors until stage 4 which is an adrenal crisis!)
You may want to do a search for this as well.

Please note that the above is not intended as a substitute for medical advice.

Should you have any questions, please post again, or you may message me directly any time.

Wishing you well.
Niko