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Elevated SED rate and positive RA factor
Hi, I have recently been feeling fatigued and switched from a family physician to an internal medicine specialist. She found that I have an elevated sed rate of 43 and then I tested positive for RA (24 on the Mayo Clinic scale). I will see a Rheumatologist this week. Oddly, I have no pain or stiffness in my joints. All other blood work looks good and I had an MRI last week to rule out a brain tumor or lesions on the brain (often a sign of MS). Any thoughts on what other issues could be going aside from the possibility of RA? Thanks!
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1268057 tn?1462734870
This factor can be elevated with other conditions/diseases as well.  Just google elevated RA Factor.  Does not necessarily mean you have RA because you have a positive RA Factor.
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351246 tn?1379685732
Hi
Welcome to the MedHelp forum!
High levels of rheumatoid factor can be found in severe rheumatoid arthritis, autoimmune diseases like systemic lupus erythematosus (SLE), scleroderma, Sjögren's syndrome, and vasculitis, infections like Hepatitis-C, chronic diseases like tuberculosis, mononucleosis, syphilis, and malaria, leukemia, liver disorders and endocarditis.
RA of 24 is not very high. It may not mean anything. An elevated ESR just confirms inflammation in the body and is not very high either. If you are feeling fatigued then you should rule out certain other conditions such as hypothyroidism, anemia, chronic fatigue syndrome, depression, poor sleep patterns, inadequate sleep, low Vit b12, low iron, low calcium, sodium and potassium.  A comprehensive investigation is required keeping all the points in mind.
Hope this helps. Please let me know if there is any thing else and do keep me posted. Take care!
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Avatar universal
Thank you so much for your help and support!
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Avatar universal
Hello again, I saw an excellent rheumatologist and he ordered $3200 in blood work and a chest scan. Specifically, we are looking into these possible disorders/disease scenarios that could be driving up my SED and RA numbers: lupus anticoagulant syndrome, sarcoidosis, inflammatory bowel diseases, celiac disease and hepatitis b and c. I am still very fatigued and anxious. My doctor promised to smoke this out, so I am confident that he is looking at all angles. Again, thank you for your support! This is a very comforting site for those seeking answers and help!
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