I don't understand-Can anyone help?

[imbranded]

I am a 25 yr old female. Up until May 30, I had not had a menstral period since January. I have had all of the classic "menopause" symptoms: night sweats, hot flashes, mood swings, etc. In April, my GP did labs and found that my FSH & LH levels were very elevated (FSH=61.9 & LH=61.7), my GFR was at 80 (116 is normal) and that my SGPT is at 86.4 (2-40 is normal) and referred me on to a GYN. My GYN said that my Ovaries had definately stopped working, and diagnosed me with Premature Ovarian Failure. At that visit, on May 30th, he did a pelvic exam, and prescribed Hormone Replacement Therapy. Before I could even take the first pill, I started bleeding. I have yet to stop, and today is June 26th. We did an ultra-sound and it revealed that there was a follicle in one of my ovaries, and that I had Fatty Liver. He also did a Glucose Tolerance Test and said that I was insulin resitant. The pap came back positive for HPV, and showed Dysplasia. He has scheduled me for an Colposcopy.The GYN said that I couldn't have POF because of the follicle and when asked about the Fatty Liver, Liver function and Kidney function tests, and PAP results, he told me that everything was independent of one another. I don't understand what is going on, but I am not sure that all of these things are just coincidences.

Does anyone have any information to give, or any sugestions?

Thanks

[medicmommy]

A PS...Also, if you haven't, get your blood checked for Hepatitis C...Even if you are low risk, and you can't think of any possible way you could have gotten it, it's a good thing to rule out just because of the fatty liver and elevated SGOT...Best wishes...~Melinda

[medicmommy]

The PTH is a blood test of your Parathyroid hormone levels. Interesting you mention kidney issues, because one of the symptoms if hyperparathyroidism is kidney stones...I had the misfortune of having 7 in 2 years! (I've had natural child birth with labor that lasted 45 hrs and the kidney stones were definitely worse!) Check out Parathyroid.com...If it is hyperparathyroidism, it's usually caused by a benign tumor that grows on one of the 4 parathyroid glands. All the parathyroid hormone does is regulate your blood calcium. When the PTH is elevated, it makes your bones give up calcium to supplement the blood levels. When it is falsely elevated because outside influences (eg. a tumor) your blood gets too much calcium and your body has to get rid of it...The primary way it does this is by filtering it out through the kidneys...When the kidneys get overwhelmed, the calcium builds up in your blood...and begins wreaking havoc on your system...The pelvis "aching" you describe, may very well be bone pain from your pelvis having to give up calcium from it's stores...
I didn't mention...I went through a very similar experience that started when I was 38 yrs old...when I went in to my Dr., I got a placating pat on the hand and was told,"Dear, this brings everybody in...It looks like you are perimenopausal." That was 4 YEARS before they symptoms got so bad, that I was hospitalized and was re evaluated by a different Dr.!  (I discovered my calcium levels were elevated even back then!) Don't let this happen to you! Even if it isn't HPT,  your body is shouting there is something wrong! Take care...Keep us posted on what you find...   ~Melinda

[imbranded]

First of all, thank you so much for your kind words. I have had frequent urination, headaches, and ALOT of abdominal/back pains. I have had pyelonephritis (kidney infection) many times, and the pain is in the middle of my back. My pelvis hurts... I know that sounds strange, but that is exactly where it hurts, right below my c-section scars. Everything feels yucky. That's the only way I can explain it... I just don't feel good. I haven't had my PTH, but the doctor did a T4 and T3 test and it came back in normal range. What is it?

[medicmommy]

At 25, with these symptoms, be sure to see an endocrinologist...Just curious...Do you know if your blood calcium levels are elevated? Any problems with frequent urination, headaches, and unexplained back and abdominal pains? If so, have your PTH level checked. It is pretty unusual for this to be elevated, so most docs don't think to check for it...This would indicate hyperparathyroid problems that elevate your calcium levels and effect every other organ in your body...Including your hormones that control your reproductive areas...Get copies of all your tests (blood and others) and pack them with you to Dr appts...it will help you be an advocate for yourself...The more tools you give a DR to work with, the more accurate your diagnosis will probably be...Good luck..By the way, I've had a culposcopy..No biggie...:) The odds are in your favor that it's nothing serious...

[wishforchange]

I don't know if this helps, but symptoms of insulin resistance, irregular or absent periods, and persistant bleeding are all typical symptoms of polycystic ovarian syndrome.  I would hope you have been evaluated for this but would double check to be sure.  Insulin resistance can cause changes in many other organs and for what it's worth I agree this is all unlikely to be coincidence.  If your gyn is insistant on not wishing to take other ideas on board you are absolutely entitled to get a second opinion, or as many opinions as you like.  At 25 you have a long reproductive life ahead of you, please don't let any doctor dismiss any of your symptoms.  You need to perhaps be assertive, but polite, in asking for answers, and persist.  It sounds like you are already on the right track by questioning their finding.  Let us know how you get on.