Symptoms began after one month on zocor. Blood test "normal". Continued on with meds for 3 more months then called Dr.Was told to stop zocor. Waited about 3 months to see if things improved. Legs muscles were tightening and legs feeling tired. Called Dr., blood tests done, "normal" with slight increase in CPK. Dr is spinning me off without any diagnosis to a rheumatologist in another town. My suspicions...zocor caused myositis. Am I the only one who's had this "rare" side effect? Doubt rheumatologist will help here and the clock is running. PLEASE HELP! Is there a doctor in the house?
You have to look at two possibilities here, Myositis, and Myopathy. The symptoms are very similar, but Myositis is autoimmune, and Myopathy is neurological. The rheumatologist should run a full autoimmune panel including SED-rate. This should indicate whether or not you have an autoimmune reaction going on. If not, then hurry up to the Neurologist. In fact, if you think it may take a long time to get the appointment with the Neuro. get the referral now, and make the appt. right away. You can always cancell if you don't need to go. You need to get an EMG. This measures electrical activity in your muscles. You will also need your blood potassium level checked, and may need a muscle biopsy to confirm the diagnosis. hopefully, it will be reversible. Here are some links that iI hope will help. Good luck.
You may have looked at this 1st link already, but read it carefully again.
This one refers to the muscle wasting as Myopathy, and also has a quick list of all the drugs not to take with Zocor.
This link, if you look at the last section labeled "Hypersensitivity (Allergic) Reactions" It says that Zocor can cause a reaction that mimics Lupus, which like Myositis, is an autoimmune reaction.
This link talks about Myopathy.
It doesn't (as far as I can tell) cause an actual autoimmune disease. It can cause Lupus-like symptoms. Look up "Drug-induced Lupus" for a better understanding of what I mean. The symptoms usually abate over a period of time once the drug is completely out of your system.
This site complies with the HONcode standard for trustworthy health information.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.