Undiagnosed Symptoms Community
Low Anion Gap
About This Community:

This patient support community is for discussions relating to undiagnosed symptoms, breathing difficulties, feeling cold, cough, diarrhea, dizziness, fainting, fever, indigestion, itching, nausea, numbness, pain (chronic), paralysis, rash, sweating, swelling, urination problems, and vomiting.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Low Anion Gap

I have regular labs due to metastatic breast cancer.  My CMP is usually normal, however, my anion gap has been decreasing.  In March it was 12, in April it was 4, and this week, it measured at 2.  My doctor is not concerned.  From what I have been reading, it appears that follow-up is necessary.  Would you recommend to someone that has labs like mine to request further testing.  Would this be urgent?  And lastly, what could cause someone's AG to continue decreasig?

Thank you for your help.
Related Discussions
3 Comments
Blank
Avatar_n_tn
Is a reading of 6 Anion Gap a problem,?
Blank
351246_tn?1379685732
Hi
Thanks for writing to the forum!
“The average anion gap for healthy adults is 8-12 mEq/L. Unlike a high anion gap, obtaining a low anion gap is relatively rare. One of the most common causes of a low anion gap is a low albumin level (which constitutes ~80% of the unmeasured anions). Correspondingly, an increase in the number of cations, either organic (eg, paraproteins as in multiple myeloma) or inorganic (bromide, lithium, Iodine or polymyxin B) can lead to low anion gap values. A decreased anion gap is also seen in multiple myeloma where the increased negatively-charged immunoglobulins interact with and bind cations in the blood.”
Refer: http://en.wikipedia.org/wiki/Anion_gap

Hope this helps. Please let me know if there is any thing else and do keep me posted. Take care!
Blank
Avatar_m_tn
A related discussion, anion gap was started.
Blank
Continue discussion Blank
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Undiagnosed Symptoms Community Resources
RSS Expert Activity
242532_tn?1269553979
Blank
How to Silence Your Inner Critic an...
Apr 16 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Emotional Eaters: How to Silence Yo...
Mar 26 by Roger Gould, M.D.Blank
1344197_tn?1392822771
Blank
Vaginal vs. Laparoscopic Hysterecto...
Feb 19 by J. Kyle Mathews, MD, DVMBlank
Top General Health Answerers
4851940_tn?1385441629
Blank
jemma116
United Kingdom
Avatar_f_tn
Blank
mkh9
CA
1340994_tn?1374197577
Blank
Caryopteris
Raleigh, NC
Avatar_f_tn
Blank
silverfox67
Clifton, AZ
1756321_tn?1377771734
Blank
Red_Star
Queensland, Australia
Avatar_f_tn
Blank
bonijokrauss