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Zanaflex and Liver Enzymes
I am scheduled for surgery next week, however, I just failed Medical Clearance due to elevated liver enzymes.  I have been on zanaflex (6mg at bedtime) for 3 months.  My internal doctor said there is a correlation between zanaflex and elevated enzymes.  As a result, I am going for a repeat blood test and my surgery is postponed.

Please has anyone had a similar experience with elevated liver enzymes because of ZANAFLEX???

Thanks!!
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351246_tn?1379685732
Hi
Welcome to the MedHelp forum!
If you have a muscle problem then AST can rise even without medication. Also Zanaflex is metabolized through liver and can cause raised liver enzymes. Also if you have an existing liver impairment you can expect the liver enzymes to rise further with Zanaflex.
Hope this helps. Please let me know if there is any thing else and do keep me posted. Take care!
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