My husband has been treated with isoniazid & rifampin for bcg cystitis for 10 days now. The infectious disease MD did not want to add steroids at this time. He has continued prosed DS and Sanctura XR that his urologist prescribed, though we do not know which of these is providing the 10-20% improvement in his symptoms. His bladder cancer was diagnosed 8 yrs ago. he had a recurrence 4 yrs ago and the Bcg was successful until 5/08. he has since had an 6 wk course of bcg...then after a month or so 3 weeks of "maintenance" bcg. These were progressively tougher on him, thus he was given 1/2 dose for the 3rd dose (completed 4 wksago). He subsequently never had relief of the bladder spasms, urgency or frequency...thus the current tx. Would this be the course of tx you would recommend? Should he continue the prosed and Sanctura..how do we know what's working...and how long before he feels more than 10-20% better!!?
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