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First off, I am a 29 year old female.  I am currently on Prevacid(60mg), Lisinopril(10mg), and have been on Depo-Provera for 4 years.  About 10 months ago I began having severe back and stomach pains which I am still living with.  My gastro has been treating me with 60mg of Prevacid a day(though the pain persists).  Not long after the back and stomach pain began, I noticed an increase in my daily urination.  This has gotten progressively worse.  I wake up at least 10 times a night to urinate.  During the day, I can go every 10 minutes or so.  I've also noticed that I "leak" a bit during the course of the day.  Also, my first void of the day is accompained by stomach burning and pain.  Needless to say, my quality of life stinks.  I can't work, can't even go to a mall or restaurant.  I have had a urinalysis which was negative, STD tests negative, and an ultrasound of my ovaries was negative as well.  I wonder if this might be a reaction to one of my medications or if it's stress or what?!  I thank you so much for any help you could offer.

[Kevin Pho, MD]

Hello - thanks for asking your question.

You note frequent urination with a normal urinalysis, STD screen negative and negative ultrasound of your ovaries.

There are a variety of causes that can cause urinary incontinence and frequent urination.  I would first check a blood sugar level to make sure that diabetes is not present.

Renal function tests, calcium, and a vitamin B12 levels are other blood tests that should be checked.

Tests for a postvoid residual (i.e. using an ultrasound to see how much urine is left in the bladder after voiding) should be performed to further evaluate the cause.  

The most definitive test would be urodynamic testing.  These series of tests can evaluate an deficiencies in the musclature affecting urination.  A urologist can describe various pelvic exercises that can improve the symptoms.

As far as I can see, your medications should not increase the frequency of your urination.

Followup with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Thanks,
Kevin, M.D.

[Silver birch]

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