Bladder findings....can this indicate anything other than MS?

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  HI, Doctors. I wanted to get your input on the following. I have had negative MRIS, EVPS, and a negative lumbar puncture. Had all sorts of bloodwork come back negative, with the exception on the antinuclear antibody. Other than that, the only thing found to be "consistent with MS" is bladder testing. I have three questions listed below:
  My report says: Impression: hyperreflexic neurogenic bladder with uninhibited hyperreflexic contractions. Uninhibited bladder contractions of unclear etiology, there is no primary bladder source to account for these such as infections, stone, ulcer, caruncle or other abnormalities of the bladder or bladder lining. These findings are consistent with the very early symptoms of MS.
  MY QUESTIONS: As my doctors say my other symptoms are not typical of MS, doesn't this report pretty much verify that MS is the only thing that could be left to cause this problem? Are there any other things that could cause this? Is this the same as an irritable bladder?
  Thank you for your guidance. I recognize that you cannot give medical diagnoses on the internet, but I do respect and appreciate any input you can give on this matter.
  Charlene
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Dear Charlene:
MS is one of the most common neurologic diseases causing voiding dysfunction.  The disease is caused by an impairment of the conduction nerves, and  50-88% of patients with this disease complain of some type of urinary tract dysfunction at some time during their disease process.  Bladder involvement is part of the initial presenting symptoms in approximately 10% of patients.  The primary urological findings include, an overactive bladder which contracts when it is not supposed to, a non-functioning (atonic) bladder that cannot squeeze at all, or a bladder that can contract, but the sphincter or valve to empty the bladder won’t open properly.  There are many other non-urological symptoms that may be associated with multiple sclerosis.
The urodynamic result you mentioned essentially reports that you have an overactive bladder.  This may be caused by a variety of neurologic (Multiple sclerosis, Parkinson’s disease, stroke, spinal disk compression, etc.) and non-neurologic conditions ( such as urinary infection, stones, etc.).  Although you don’t exhibit the classical symptoms of multiple sclerosis, this does not mean that you don’t have multiple sclerosis.  Your doctors may not have diagnosed it at this time.  Therefore, it would be wise to continue following up with your neurologist and urologist. Multiple sclerosis may take time to diagnose as its manifestations may not occur all at once.  In addition, keep in mind that many other conditions can result in hyperreflexia or an overactive bladder.  Hope this information is useful to you, and wish you the best.
This information is provided for general medical education purposes only.  Please consult your physician for diagnostic and treatment options pertaining to your specific medical condition. More individualized care is available at the Henry Ford Hospital and its satellites (1 800 653 6568).
Sincerely,
HFHS M.D.-JJ
*Keyword: multiple sclerosis, hyperreflexia, overactive bladder