Frequency 8-12 times a night

  
  My wife has Multiple Sclerosis. It turned nasty this past year. One of the noticeable symptoms has been a bladder problem. She had a number of bladder / UTI infections. Also has increased frequency and urgency to urinate. We are up 8 to 12 times a night. The lack of sleep is a killer!
  My wife ended up in the hospital for a couple of months. Same frequency and urgency to urinate drove the staff nuts. Every time they measured her bladder, it was less than half full, consistently, but she had the urge.
  She is now back home and we are still dealing with it. The urologist performed a videourodynamics test. He said the bladders not functioning, nerve signals not getting through. Disconnected somewhere in the spinal cord/brain. Her bladder is full all of the time, a turn or strain causes the urge to empty (bedtime). Low liquid consumption sets her up for infections