IC

  I had a DMSO instillation 2 weeks ago.  I felt worse for 1 1/2 days; then for four days I felt really good.  Now I am back feeling worse than before I had the treatment.  Does DMSO do any damage to the bladder lining?  Would a DMSO cocktail (DMSO, steriod, and sodium bicarbonate) be better?
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Dear Sharon,
I Interstitial cystitis is a disorder that affects  approximately 43,500 women in the United States. It is characterized by pain, frequent voiding , burning and urgency in the absence of any evidence of infection.. Treatment is largely directed at alleviation of symptoms. Many drugs have been evaluated in the treatment of IC. Recent attention has been given to Sodium pentosanpolysulfate ( Elmiron), tricyclic antidepressants such as amitryptiline, and bladder instillation with various agents such as DMSO and BCG. DMSO has been utilized since it was first poularized in the 1960