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Urology  (Expert Forum)
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IC
Questions in the Urology forum are answered by Dr. Stephen Liroff, affiliated with the Henry Ford Hospital. Topics covered include benign prostate disease, penis curvature, cystisis, kidney stones, pediatric urology, prostate, sexual dysfunction, urinary tract infections (UTI), and urological cancers.

IC

by sharon__0__0, Jan 03, 1999 12:00AM
  I had a DMSO instillation 2 weeks ago.  I felt worse for 1 1/2 days; then for four days I felt really good.  Now I am back feeling worse than before I had the treatment.  Does DMSO do any damage to the bladder lining?  Would a DMSO cocktail (DMSO, steriod, and sodium bicarbonate) be better?
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Dear Sharon,
I Interstitial cystitis is a disorder that affects  approximately 43,500 women in the United States. It is characterized by pain, frequent voiding , burning and urgency in the absence of any evidence of infection.. Treatment is largely directed at alleviation of symptoms. Many drugs have been evaluated in the treatment of IC. Recent attention has been given to Sodium pentosanpolysulfate ( Elmiron), tricyclic antidepressants such as amitryptiline, and bladder instillation with various agents such as DMSO and BCG. DMSO has been utilized since it was first poularized in the 1960’s. It  has a success rate of about 60 to 80 % . However , the relapse rate is high. Many patients get better for a short duration of time and then require further treatment. In your case, it would be advisable to explore all of your options with  a physician that specializes in this condition.
Evaluation by a urologist that specializes in interstitial cystitis is worthwhile as they have access to various experimental protocols not available to the average urologist. It is very common for patients with IC t o average 4 physicians before the diagnosis is correctly made. To contact a physician in your area call the Interstitial Cystitis Association ( ICA) (212) 979-6057. This information is provided for general medical education purposes only.  Please consult your physician for diagnostic and treatment options pertaining to your specific medical condition. More individualized care is available at the Henry Ford Hospital and its satellites (1 800 653 6568)
HFHS M.D.-KR
*keyword: interstitial cystitis





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