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Is Testicular Atrophy Reversible?
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Is Testicular Atrophy Reversible?

My husband was diagnosed with low Testosterone levels in 2000.  He started on patches and later injections of supplemental testosterone.  Our doctor never did any other hormone testing and his levels were not checked on a regular basis.  We conceived a child in 2003 and she was born in 2004.  Recently we had fertility tests done as we have not been able to have another child.  It was found that he had azoospermia.  He also has a great degree of testicular atrophy.  We are obviously devastated.  My concern is whether or not this can be reversed and if we will ever again be able to have a child.  Should he stop the testosterone?  The whole situation is extremely confusing and frustrating.  I would be grateful of any help/advice you could give.  Is there a light at the end of the tunnel?
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Avatar_dr_f_tn
Hi,

Testicular atrophy is a side effect of treatment with testosterone and occurs due to the suppression of the normal hypothalamic-pituitary-gonadal axis.

This side effect is best treated if it has been diagnosed in the early stages. A few treatment options include treatment with human chorionic gonadotropin and cessation of testosterone treatment.

HCG treatment can involve 5000 units in one week or 1000 units every other day and are administered after complete cessation of testosterone supplements.

Do post here for any further doubts in this regard.
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Avatar_m_tn
can you reverse testicular atrophy without completely stopping testosterone therapy?  when I noticed that my testicles were shrinking, I went off androgel (10 g. daily), for four days.  by the end of the four days, they were pretty much back to normal size.  back on treatment, one month later I tried again, but they are taking longer to restore this time.  can you trick your testicles into thinking they need to keep producing, and thus stop shrinking, by cycling in and out of synthetic testosterone treatments? if so, is this safe?  I need the testosterone, but the atrophy is also very distressing.
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Avatar_m_tn
Eight years ago deep, and very dark depression forced me to ask my urologist to check my thyroid as I've never been moody. He checked testosterone too, and multiple tests at different times of day showed it was quite low, barely above 100. So he put me on andogel which had a dramatic effect on mood, the depression vansihed, never to return.

The testicular atrophy I have isn't really a problem per se, as I'm 67 and have all the hormone needed to function more than satisfactorily, to my wife's occasional chagrin.. But they have shrunk to be amazingly small, somewhat larger than peanuts, and the scrotal sack has responded accordingly, being almost flat againt my perineum.

Would the testicles ever bounce back to normal size with supplementation cessation, or is this a permanent condition after eight years?
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Avatar_n_tn
Many in the body building community use HCG ( human chorionic gonadotropin ) while using steroids and Toremafine Citrate afterwards to help restore function. While Toremafine Citrate is not without some pretty severe side effects if one is trying to concieve (conceive) the use of HCG should definatetly be done, and in my humble opinoion Toremafine Citrate or another selective estrogen receptor modulator might be worth considering after stopping the testosterone and giving it time to clear the body ( usually about a month with the esters used in TRT) the inclusion of Toremafine may make the difference you need to get the testicals functioning.

By the way you can do a search on PubMed to see studies of the use of Toremafine Citrate as well as other SERM's in clinical trials, I certainly don't expect you to take the word of an internet body builder on something so serious.
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Avatar_n_tn
my brother married since 3 months and now with seminal analysis he discovered azoospermia  and by us discovered mild testicular atrophy. can i ask what another investigation can we do ? and if there are a hope to get even a one child ? if we take testicular biopsy can we find sperm viable for in vitro frtilization ?  
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Avatar_n_tn
my brother married since 3 months and now with seminal analysis he discovered azoospermia  and by us discovered mild testicular atrophy. can i ask what another investigation can we do ? and if there are a hope to get even a one child ? if we take testicular biopsy can we find sperm viable for in vitro frtilization ?  
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Avatar_n_tn
I have been suffering from shrunken, aching testicles and low sex-drive after a testicular trauma two years ago, and have recently been diagnosed with chronic epididymitis. Is there any treatment to reveerse the resulting testicular atrophy?
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Avatar_f_tn
In a previous reply you stated the use if HCG for Testicular Shrinkage.. How long & at what dose should I use it.. Would 200 U per day for 25 days be sufficient?
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Avatar_m_tn
Hi I am Dost11 , please Dr , I am 23 YO by the chance some doctors told me that i have Testicular atrophy ,, so i am so scared what can i do ?  that was in 2011
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Avatar_n_tn
hi i m 32 years old and diagnosed  Testicular atrophy from 1 year i m on hcg and misterlon but the last seminal analysis still azoospermia ,, so i am so scared what can i do ?  
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Avatar_m_tn
I am 38. I can not remember since when I have testicular atrophy.
The urologists I visited told me there is no cure. I have to live with testicular atrophy. I have also azoospermia. My LH value is 14 mIU/mL. My testicle size is 8 ml. My urologist told me I should have more than 14 ml sized testicles. The urologist told me that my testosteron is at the lower end but in the normal range. As far as I understand I do not have much hope to improve my situation. I did no HCG treatment but I am not sure that HCG treatment is right for me.

Am I right? There is no hope that I can cure my testicular atrophy.
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Avatar_m_tn
Did the hcg treatment increase the size of your testicles? And what happened after you stopped  hcg treatment? Did the testicle size decrease?
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Avatar_m_tn
In 1981 I had a vasectomy. Since then, I have learned that this can  cause a big drop in T. My doctor tested me and said I am very low, putting me on T injections every three weeks. Nothing was ever said about atrophy, but lately I have noticed a HUGE decrease in testucluar size, just as reported here by others. SInce my baby-making days are long over, I am not concerned about my fertility, nor even for the cosmetics of the situation. But, I am concerned about my overall health effects and long term results. At 73 I'm just not too concerned about my balls. I realize I need to lose some of these pounds, which may have cause much of the low T in the first place. So, my question is: do I need to be doing anything differently? My libido has improved considerablty since starting the injections a year ago. My wife is a bit miffed, saying it doesn't make any difference to her. This is a great site; thanks for all the good input to everyone.
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Avatar_m_tn
Hello
I'm 20 and recently suffered from mumps and then Orchitis..

Now i personnaly perceive that im suffering from testicular atrophy in left testicle..
is it reversible??

or will it cause any long term disability like infertility..??
Thanks
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Avatar_m_tn
i have the same problem i am crying all the night cause there is no chance to have a child an and i am single child in my family this means that  there will be the no trace of my family after my death!
My God Please Help me!!!
Pleas  anyone help!!
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Avatar_m_tn
I am 22 years old, i have been taking Soya products since 18years. Now today i realize that i had bad effects for men. Soya products start producing mammary glands in men, lower the level of testosterone. Today i found that i had shrunken testicles, even the size of my penis is small, lower testosterone production, even my body is very sensitive as girls, etec. Please help me how i can overcome this problem naturally or by any way??
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Avatar_m_tn
when i was 17 years old i took steroids. i was not fully developed yet and never new about PCT's or Serms. The effects of atrophy set in and i never thought much about it after 8 years i started feeling tired , weak , no drive n life and low libido . so i went to the doctor and had a 298 test level thay put me on Test - Depo / Cypinate every 14 days i told the doctor that i didn't need this that i need my own testicles to  function normally again and that this was the reason i had low test in the first place he told me that his treatment was the best option i argued and placed many phone calls to specialist and did tons of research and found out that i had made a huge mistake when i was 17 and was an idiot. But i found out that there was people just like me so i contacted them on line and forums found a patient being treated for it who taught me every thing and gave me a treatment that worked for him so i took it to my doctor and said this is what i want to do help me or i will find a new doctor. i gave him all my research and we decided it was possible to work but it would be very aggressive and will have side effects. at this point i was desperate and running out of options. I was to stop the T shots and Take HCG for 1 and a half months then  start with nolvadex for 3 weeks then switch to clomid for 3 weeks. so i did. Best choice of my life It was very aggressive i had a few mood swings but i controlled hem well used exercise to help. After the treatment my testicles grew back to all most 100% normal size my libido was of the charts rock hard boners BTW  and My test levels were sustained around 750-850. Since this i have had tons of energy and sex drive as well as feeling confident again. And i just wanna say TY to all the patients that helped me and for the record most doctors are uneducated in this field even Endo's can lack the exp for each individuals problem. Make sure you tell your doctor how you feel remember you pay them and a degree means nothing cuz thay just have basic knowledge in all areas thay rely on research and books more than there education.        
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Avatar_m_tn
So now what are you taking to make sure your balls don't shrink again and that you're Test levels stay at a healthy level.  Once you do all of this are you stuck on these meds forever???
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Avatar_m_tn
Hi, I also need the information about how to get off T and regain function and size of the testicles. Recently had testicular atrophy on the right side which I took up with my Dr. He sent me to an Uro who tested T levels which were on the lower end of the scale and he put me on T treatment. Due to the atrophy the sperm count is also low. Could you email me all research and info you have regarding getting off the T and try getting the size and function increased.
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Avatar_m_tn
hiiii cud u please gimme the contact details of the doctors who treated u...plz email me  ***@****.... i have atrophy testis ...thnx
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Avatar_m_tn
I'm curious, what were the dosage levels for all, please. i.e. HCG, Nolvadex and Clomid? Am about to have the same conversation with my Urologist!

Thanks
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Avatar_m_tn
MY TESTICLES HAVE REDUCED CIGNIFICANTLY IN SIZE I AM SUICIDAL WITH DEPRESSION BEEN TO DOC STHEY SAY NORMAL BUT THEY ARE NOT AND CONTINUE TO SHRINK HELP HELP HELP
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Avatar_m_tn
Hi TheHelp I hope you receive this message, I'm Miguel and I had exactly the same experience you had. I need to contact you to get more info about your research. So far I have done a big research too but your experience is really similar to mine... My email is ***@**** I'm going to see my endo next week and I would like to discuss with him about the treatment you got. God bless you for your help!
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Avatar_n_tn
I am 59 yrs old . run and work out pretty reg. I have been taking testostrone pellet injections.My wife takes and it works great for her lack of estrogene . she had a full historectomy years ago.
so i starten getting the injections.
I saw a youtube video on testicular shrinkage. and started paying attention. starting to shrink after 2 years {about}
The dr. was sports medicine for ?? maybe olympic team. He said the real solution is to block something???  thus allowing the testicles to do their job and this medicine would block the testosterone blockers. or maybe he said that it stops the estrogene, and; it would give same effect as testosterone.
can i just go to a local dr. and get the hcg  ?? thanks for the comments and help.
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Avatar_m_tn
I have been on T pellet injection therapy for about 2 years and have notice my testicles shrinking in the last few months.  I'd like to get your research so i can take it to my doc.  Can you send it to ***@****?  Thanks
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Avatar_m_tn
Hi TheHelp. I have also experienced the same things. Please send also to me your research findindgs. my email is ***@****. Please HELP.
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