Nonbacterial irritated urethra or prostate?

Does anybody know whether it is possible to have an irritated urethra and/or prostate not caused by a bacterial infection?  I have recurring symptoms that involve a burning pain in the urethra and slightly more frequent urination.  I have had a full work up with a very good urologist including a cystoscopy.  Nothing has been found through these tests other than an area in the back of the urethra where urine pools.  That sounds worse than it is and is apparently not harmful.  I also have a spermatocele.  I have not tested positive for any bacteria even when the symptoms were subjectively severe.  I wonder if it is possible that I am somehow irritating the urethra and/or prostate by something I am doing sexually (such as too much or not enough masturbation or sex with my wife) or by something I am eating or drinking or some other activity such as bike riding.  I believe there is possibly a correlation to masturbation. It also seems that with time the problem subsides only to return again.  Any thoughts on this?

[Pegmom3]

I am a 30 yr old female who is having VERY similar symptoms! I have been going to the docs and so far they have found no infection,and are kind of giving up. I have been to two dif docs a gyno and family doc, both have not been able to figure anything out. For me the discomfort comes and goes,bothers me for a day or so then gone for a couple days, then back again. I too believe masturbation may have something to do with this problem. All the doc told me was to take otc AZO,helps the urethral discomfort and helps control frequent bathroom visits. Please let me know if you have found anything out since you last posted,Thank you.

[Dr J Singh]

Hello,
In females, urethral syndrome is an important cause of such symptoms. It is a primarily female syndrome in which women suffer from irritative bladder symptoms (urinary frequency, urgency, burning, and a hesitant or slowed urinary stream) in the absence of any objective urologic findings.

In this the diagnosis can be made only by the proper collections of urine specimens from both the urethra and the bladder. These specimens will reveal the presence of white blood cells in the urethral washings, while the midstream (bladder) specimen will be free of cells.
I sincerely hope that helps. Take care and regards.