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Urology (Expert Forum)
Pain in the upper thighs
Answered by
Kevin Pho, MD - Internal Medicine
KevinMD.com
Questions in the Urology forum are answered by Dr. Stephen Liroff, affiliated with the Henry Ford Hospital. Topics covered include benign prostate disease, penis curvature, cystisis, kidney stones, pediatric urology, prostate, sexual dysfunction, urinary tract infections (UTI), and urological cancers.
Pain in the upper thighs
by richbrunt, Jan 13, 2005 12:00AM
I wondered what might be the aetiology of this, and thus the significance.
My tumour parameters are T2c, Gleason Score 3+4, PSA 58
Also, I'd be interested in your comments on a resent news clip on CNN stating that Hormone therapy may not lengthen life, and may cause bones to become brittle.
My tumour parameters are T2c, Gleason Score 3+4, PSA 58
Also, I'd be interested in your comments on a resent news clip on CNN stating that Hormone therapy may not lengthen life, and may cause bones to become brittle.
Doctor's Answer
by Kevin Pho, MD, Jan 15, 2005 12:00AM
, Jan 15, 2005 12:00AM
The Gleason score is used to interpret the histology of the prostate biopsy. It is a score from 1 to 5, with a higher score indicating a greater liklihood of non-organ confined disease and a poorer prognosis. One number measures the growth factor, the other the degree of differentiation. The combined score (7 in your case) would represent a moderately differentiated cancer.
A T2c stage would indicate cancer that is confined to the prostate but has involved both sides.
Hormone therapy is associated with osteoporosis - and certainly concurrent treatment to prevent this complications should be considered (i.e. fosamax). Hormone therapy has been shown to lengthen life in cases of advanced cancer in combination with radiation. The benefits with its use in combination with other modalities is less clear.
You may want to discuss this with your urologist.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
Medical Weblog:
kevinmd_b
A T2c stage would indicate cancer that is confined to the prostate but has involved both sides.
Hormone therapy is associated with osteoporosis - and certainly concurrent treatment to prevent this complications should be considered (i.e. fosamax). Hormone therapy has been shown to lengthen life in cases of advanced cancer in combination with radiation. The benefits with its use in combination with other modalities is less clear.
You may want to discuss this with your urologist.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
Medical Weblog:
kevinmd_b
Member Comments (1)
by richbrunt, Jan 15, 2005 12:00AM
To: Prostate Cancer
0
