Urinary frequency after antibiotic treatment

[Tashi]

My 5 years old daughter had a sevear tonsillitis in November. She was treated with bactrim forte first, changed to Infex after three days and receaved an Acantex-ceftriaxona injection. The infection lasted almost 10 days in which she also had Ibuprofeno every 6 hours, she wouldnīt accept to take Klosidol. She couldnīt also eat nor drink enaugh liquid because of pain in her throat.  After the last dosis of Infex, she had been given a multivitaminic tonic (Supradin). That night she waked up four times to urinate. She never wakes up in the middle of the night to urinate. After that she had been urinating several times a day. At first the amount of urine was high and many times it was colourless. After some days the amount reduced and now she urinates very small proportions each time except the firts time in the morning that the proportion is about 300 ml. Noy she only urinates during the day.

This condition was also associated with inflamed vulva due to a fungi (candidalbicans) infection which was treated with a pomade. After using the pomade for 5 days the inflamation (inflammation) reduced and for some weaks (two or three) the urinating frequency also reduced. But the inflamation (inflammation) of the vulva seemed to be back after some days and the urinating frequency increased again. I also noticed cludiness in the firt urine in the morning. Some days is worst than others and that there is like a white claudy substance that remains like floating and then sediments.

I took her to a nefrologist and many medical exams were done.  Uroanalysys, culture, 24 hours urine, a complete blood analysis and a ecography. She doesnīt have an infection and all the parameters seem to be normal except for the concentration of calcium in urine which is higher than normal for her age. However there is no calcium in blood.

Right now the only treatement she is reciving is the reduction of salt.

She is disturbed by her permanent urgency to go to the bathroom, she doesnīt want to go out if she is not sure she will be able to go to the bathroom soon. And I am worried her kidneys may be hurted by antibiotics or ibuprofeno.

Can urinary frequency be associated with hipercalcemia? What can be the causes of hipercalcemia?

Thank you very much for your attention and I hope you forgive my English spelling, grammar and lack of a more adequate English vocabulary.

[Kevin Pho, MD]

Hypercalciuria (elevated calcium in the urine) does not lead to increased urinary frequency to my knowledge.  There are some genetic kidney disorders (like renal tubular acidosis) that can lead to this condition.  

Chronic ibuprofen can also lead to kidney damage - this should be evaluated by the nephrologist.

Diabetes mellitus can also lead to urinary frequency - and this should be evaluated for via a blood test.  

You may also want to consider diabetes insipidus - where the effectiveness of ADH (a hormone that controls the reabsorption of water) is diminished.

These options should be discussed with your personal physician.

Followup with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Kevin, M.D.
Medical Weblog:
kevinmd_b

[yoshi]

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