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pyuria with sterile cultures
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pyuria with sterile cultures

  i am a 42 y.o female with a 2 year history of pyelonephritis with pan allergic responses to antibiotics with the exception of cephalosporins,aminoglycosides, and floxacins.
  i am ivp negative, cysto with dmso negative with the exception of positive cultures for lactobacillus in bladder, ureters, and renal pelvis.
  i continue to suffer flare ups of very specific left upper quadrant pain through to left flank pain, somnolence only during flares, nausea, abd pain, night sweats,weight loss. No
  lower UTI sx's. My urine consisistently shows sterile cultures, 25-50WBC's or 50-100wbcs, 25-50 squamous, large leukoesterase. Sometimes there is bacteria ,sometimes not.
  My original pyelo grew klebsiella and i was hospitalized and given rocephin and gent. I am PPD & ANA negative. CBC is mostly normal , although WBC's are 3k-4k. My urologist is
  frustrated with me as is my internist. I don't want to see doctor's anymore if it's not necessary. Should I just learn to live with it? Is there any danger to ignoring
  pyuria?. I would have ignored it this time but I lost 5 pounds in a week and it felt ominous when combined with my other sx's. I went on Suprax but with no change and have
  been sleeping for 3 days. I have no fever that I am aware of .  In November I had a flare up and reluctantly the doctor treated me with 120mg of gentamycin IM. Within 12
  hours I felt wonderful and the effects lasted 4 days then I began the downward spiral again. He won't give me any more. Symptoms seems worse in the week preceeding my menstrual cycle.
  I would be so grateful if you could give me a clue or just tell me to ignore it all safely.Thank you again.
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Dear M Wellsmor,
Sterile pyuria is a condition charaterized white blood cells without any bacteria.  It sounds as if you have been evaluated extensively.  Occasionally sterile pyuria is associated with tuberculosis .  This bacteria is very fastidious and difficult to culture. If you have not been tested for TB, this should be done. In addition, a CT scan is often helpful in evaluating  the cause of non-specific abdominal pain. If this is negative, then I think all major problems have been excluded. This information is provided for general medical education purposes only.  Please consult your physician for diagnostic and treatment options pertaining to your specific medical condition. More individualized care is available at the Henry Ford Hospital and its satellites (1 800 653 6568).
*keyword: sterile pyuria

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