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Urology (Expert Forum)
stage 4
Questions in the Urology forum are answered by Dr. Stephen Liroff, affiliated with the Henry Ford Hospital. Topics covered include benign prostate disease, penis curvature, cystisis, kidney stones, pediatric urology, prostate, sexual dysfunction, urinary tract infections (UTI), and urological cancers.
stage 4
by sheryl__0, Feb 28, 1999 12:00AM
hi,my husband has been told he is stage 4 kidne cancer.the onocoligst and our primary care interinst have both told us there is basicaly nothing tey can do now,other than resurce,and treat what signs he has next. my question is the dr started him on megace,[fo his breathing] both lungs are cancerious also. but isnt megace a hormone??? will it make the tumors grow faster?? and what causes th extreme swelling of his legs and feet??? the tiredness also has increased.. thank you for ay help..also what is his chances or lenghth of live???
Doctor's Answer
by hfhs M.D.-AK, Feb 28, 1999 12:00AM
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Dear Sheryl,
Modern treatment of stage 4 kidney cancer would include 5-flourouricil combined with interlukin-2(IL-2) or interferon alpha . These two therapeutic regimens may help, but importantly, with limited side effects to the patient. I did a literature search to review the use of Megace (megestrol acetate) in kidney cancer and found one study being done at Strong Memorial Hospital in New York who used the Megace because it was shown to improve quality of life in other cancer patients. In this study, they used the Megace in combination with Interferon-alpha to treat advanced renal cell cancer of the kidney.
My thoughts are that your oncologist knows that Megace has been shown to improve quality of life in other cancer patients and instead of doing nothing, they have decided to put your husband on Megace. I don’t have the ability to review your husbands case to determine if other medical or surgical therapies could be performed. Yet if your doctors state there are no further options, I can only go with their opinion.
To answer your last question, Stage 4 kidney cancer has a very poor prognosis particularly if there are metastases (spread) to the lungs. The five year survival is 0 to 10% in most studies. To better answer your question, your husbands performance status or general health is more important in the short-term. Your best source of information would be to ask your oncologist.
I am sorry that we cannot offer you more in this tough situation.
This information is provided for general medical educational purposes only. Please consult your physician for diagnostic and treatment options pertaining to your specific medical condition. More individualized care is available at the Henry Ford Hospital and its satellites (1 800 653-6568).
Sincerely,
HFHS M.D.-AK
*keyword:Kidney Cancer
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