In April 2008, I was diagnosed with a monoclonal protein of 0.2 g/dl. The diagnosis was made by a rheumatologist checking for possible Sjogren's Syndrome. The test used was a serum protein electrophoresis (both blood & urine), and the protein was identified as IgM kappa using an immunophoresis test. No other tests were done.
A follow-up serum protein electrophoresis test in Oct. 2008 also showed 0.2 g/dl but my follow-up in Dec. 2009 showed an increase to 0.3 g/dl.
Other than the serum protein electrophoresis test, no tests related to MGUS have been done. The rheumatologist feels that, because of the low level of the monoclonal protein, no other tests are necessary (except for annual follow-ups of the SPE test). Is that correct? I am concerned at the increase in the MGUS level, and am wondering if a visit to a specialist (a hematologist maybe?) would be a good idea.
I'm a 60 year old female in otherwise good health, except for IBS & osteopenia. Any advise? Thank you.
Our doctor was only looking for M protein, while Multiple Myeloma was the light chain version and wouldn't ever show the M protein. When discovered after two years of "watching" it was already stage 3.
Do your research. As long as the IgM is less than 3gm/dL its MGUS. If you have no symptoms, it is just monitored until you die a normal death. If you develope symptoms, then the fun begins. You are lucky since you don't describe any symptoms. Just hope it stays under the 3gm/dL.
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