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Diet drug safety
Answered by
Columbia Cardiology Associates Portland - OR
Questions in the Weight Loss & Healthy Lifestyle forum are being answered by James Beckerman, MD, Cardiologist. This forum is for questions and discussions relating to: cooking tricks, diet books, exercise tips, fad diets, fitness, health and hype, healthy role modeling for children, living a "green" lifestyle, medical treatments for obesity, metabolic syndrome, obesity, restaurants, smoking cessation, supplements, surgical treatments for obesity, trends in dieting, weight-related medical conditions

Diet drug safety

by yvette69, Jun 07, 2009 03:58PM
I recently gained 30lbs while on lexapro.  My doctor prescribed Meridia, and I am wondering if it is safe to take this with phentermine.

by James G Beckerman, M.D., Jun 07, 2009 08:04PM
Many physicians are not comfortable prescribing multiple weight loss medications at the same time out of concern for increased risk of side effects.  Also keep in mind that phentermine is not generally recommended in the long term.  It may make more sense to just stick with one of the weight loss medications to see if there are any beneficial effects.  It's also a good time to think carefully about how the weight loss occurred while on the new medication.
Member Comments (3)

by Enoch Choi, MD, Jun 08, 2009 11:31AM
To: yvette69
These 2 medications are in the class of amphetamines and serotonin modulators which can result in serotonin syndrome.

It's a good idea to discuss any drug combinations with your doctor.

-enoch

by coolwave, Jun 08, 2009 09:31PM
To: yvette69
i too was on phentermine and kinda hit a wall - stopped working and couldn't sleep well..  i requested meridia (big $) to replace/in addition to the phen and it gave me terrible gastric pains.  

doc then had me try the phen in the morning and diethylpropion (tenuate) in evening (where i was having sleep issues).  worked wonderfully.  i had considered asking for phendimetrizine but i read it was a schedule 3 drug and i had read a bariatric magazine article that casually linked it to pph.

phen and diethyl still working great for last 2 months!!
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