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Yes. I started on 9/24 and I weighed today and have lost a total of 10 pounds. I am under a doctors care, so I am also taking appetite suppressants and a fluid pill, I take the fluid pill 2 times per week. I get one shot at the doctors office and then he give me 3 syringes to give the shots to myself for the remainder of the month. I only take one shot per week. My doctor told me that the shots help more with losing inches. It's not a miracle shot, because you still have to do discipline, and you have to stay focused...It's not like you will just take the shot, and never be hungry, but the quick results help you stay motivated each week.