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Everyone has an opinion on meds and meds react differently in our bodies. I am 38, a little over weight and I have been battling severe Acid Reflux/GERD for the last year. I don't have a thyroid and take synthroid and I also had Ovarian Cancer(no meds needed, surgery and monthly doctor visits) and a total hysterectom). I was on Effexor for a short time a few years ago and I can't remember side effects. I remember zoloft I felt spacey and on Paxil my eyes were HUGE and I ran miles.... They were giving me this stuff because of the chemical imbalance in my body. The Effexor I believe was good- I rested more, I think. I am about to start taking it again, at least for two months and see. I start with a week of a low dose and then go to 75. I have a lot of worry thoughts and anxieties.... (I am a Christian and I know God is going to take care of me and is taking care of me and I trust Him, but I am human!!) What is your opinion really of all of this? I know some have had bad experiences, but there could have been other factors besides the Effexor..