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My breasts usually are at their largest (most swollenSwollen glands) the last week of hormone pills, but they were noticeably larger this time around (I've been taking the supplements for 2.5 weeks or so) and a small amount of white liquid oozed from one of my nipples. I should have my period in a couple of days, so I'll know more conclusively that I am not preggo then (though I surely did immediately take a test--negative). It seems likely to me that the interaction of the hormone contraceptive and the wild yam could produce this strange symptom (which was VERY brief--I can no longer squeeze anything out and it was never more than a tiny drop).
Don't know the answer, but I do know that when doing IVF, our docs all wanted us to disclose every natural remedy we were takiing. So there are definitely interactions they don't like. I'd talk to your gyn.