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Urology  (Expert Forum)
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Foamy Urine
Answered by
Kevin Pho, MD - Internal Medicine
Kevin Pho, MD Boston - MA
Questions in the Urology forum are answered by Dr. Stephen Liroff, affiliated with the Henry Ford Hospital. Topics covered include benign prostate disease, penis curvature, cystisis, kidney stones, pediatric urology, prostate, sexual dysfunction, urinary tract infections (UTI), and urological cancers.

Foamy Urine

by JDHAWK, Sep 24, 2006 12:00AM
Hello,



I was Dx with small fiber neuropathy two years ago. The first symptoms started about 5-6 years ago. I take Methadone, Lyrica, Cymbalta, and Hydrocodone to manage the pain. I also take several other medicines. I am a 49 year old male who drinks little water. This past summer I started to notice foam in the toilet each and every time. My (PCP) Primary Care Provider felt it was from all the medicine that I take. My creatinine was 1.6 in July and after a re-test it was 1.4 in late August which is normal for me. My BUN was 17. To date my nero has not found the reason for my neuropathy. He has suggested Amyloidosis, but feels it would have shown itself by now. I have no symptoms of an Amyloid. I am pre-diabetic, my A 1 C was 5.6. My PCP has given me a Rx for a complete blood work up. He said if the creatinine is high, he would order a 24 hour urine collection looking for protein. This is where I get scared! Amyloidosis is an illness that deposits protein on the bodies organs and foam in the toilet is a sign of protein leaking from the Kidney's. I was tested for Amyloidosis about 18 months ago and the result was negative. My PCP thinks my neuropathy is genetic. My dad and uncle both had neuropathy. My dad did develop diabetes years after his neuropathy started.



Dr., do you think that taking several medicines could cause foam in the toilet?



Do you also think that Amyloidosis would have shown itself by now (5-6 years after symptoms)?



Thank you.

by Kevin Pho, MD, Sep 25, 2006 12:00AM
Medications uncommonly may lead to foamy urine.  I agree with a 24-hr urine collection looking for protein if the symptoms continue.  



Amyloidosis also can present like this - although this is an uncommon disease.  Given a negative test 18 months ago, it would be unlikely that this is present.  Repeating the test can be considered if this diagnosis is still in question.  



These options can be discussed with your personal physician, or in consultation with a nephrologist.



Followup with your personal physician is essential.



This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.



Kevin, M.D.

kevinmd_
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