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Mood: Hope75 in a remission or getting better? Went to John's Hopkins and got some answers - see journal for details:) Journal Entry: "I finally did it - went to Hopkins and go..." [Read]
Mood: April2 is tired and now I have to take my 4 year old back to the doctor. Sigh Journal Entry: "I'm noticing the last month or so that mo..." [Read]
Smilerdeb Female, 48 years Melbourne - Australia Member since May 2008
Mood: Smilerdeb saw her Sister from the Uk after 20 years of not seeing her! I have Graves, she has Hashi's (unaware to me until today) Journal Entry: "Well my new labs came back yesterday by f..." [Read]
Paxil is less stimulating than the other SSRI's, which is probably why you had a negative response to Effexor-XR, Lexapro, Cymbalta, Prozac, and Zoloft, all of which respond more favorably to depression.
Switching to another drug class will often re-establish effectiveness. The Tricyclics (Elavil, Sinequan), the Tetracyclics (Remeron, Trazodone), or the Benzodiazepines (Klonopin, Librium, Valium) are all options. Klonopin has the greatest advantage if the primary component is anxiety.
There is little doubt that a hormone imbalance could've played a role as well.
Ryan