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Breast Cancer  (Expert Forum)
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Fibroepithelial lesion with cellular stroma
Questions posted in the Breast Cancer Forum are answered by medical professionals from The Cleveland Clinic. Topics include Breast Biopsy, Chemotherapy, Hormone Therapy, Lumps, Lumpectomy, Lymph node dissection, Lymphedema, Mammograms, Mastectomy, Radiation Therapy, Reconstruction, Self Breast Exam, and Surgery.

Fibroepithelial lesion with cellular stroma

by millie1980, Apr 21, 2006 12:00AM
I am a 25 year old woman who recently found a large lump in my right breast.  After having it ultrasounded & mammogrammed I was told that I had a 3 cm mass that was probably a fibroid & was ordered a biopsy.  Now, after the biopsy I am told that what I have is a Fibroepithelial Lesion with cellular stroma and that it will have to be removed.  My doctor mentioned that it might be a Phyllode Tumor.  My question is can they tell this is a Phyllode before excising it and if it is a Phyllode is this something that I need to be overly concerned about? I have been doing a lot of research and what I have found is that PT's are very rare and usually only occur in women 45+ but they can be malignant & often reoccur.  I'm totally confused is a PT considered a fibroid?

by CCF-RN,MSN-rf, Apr 21, 2006 12:00AM
Dear millie1980:  The term phyllodes tumor includes a group of lesions of varying malignant potential ranging from completely benign (non-cancerous) to fully malignant (cancerous) sarcomas.  It is not the same thing as a fibroadenoma.  If there is something concerning about the biopsy or the way the lesion appears, it may be that the doctor feels that a needle biopsy may not be adequate and that removing the entire area will be the better choice.  You might ask for a clarification from him/her.

IF it is a phyllodes tumore, approximately 20% will recur locally if removed with no margin or a margin of a few millimeters of normal breast tissue, regardless of whether they are benign or malignant. A wide excision with a 2cm margin of normal breast tissue is appropriate therapy for benign and borderline phyllodes tumors unless they are so large that this is not cosmetically feasible.

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