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Mental Health  (Expert Forum)
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Whant to stop taking cholinesterase inhibitor
Questions posted in the Mental Health forum are being answered by Dr. Roger L. Gould, author of the Mastering Stress and Depression program and affiliated with the UCLA. Department of Psychiatry. Topics covered include anger, attention deficit disorder (ADD), bipolar disorder, dementia, electroconvulsive therapy (ECT), learning disabilities, memory, obsessive compulsive disorder (OCD), panic, personality disorders, phobias, post-traumatic stress disorder (PTSD), schizophrenia, stress, transitions, and work problems.

Whant to stop taking cholinesterase inhibitor

by Mario Clouâtre, Mar 23, 2000 12:00AM
After consulting 2 specialist, my mom (65 y.o.) was diagnose with begining AD by one of them. She has a long story of memory problem. Myself (age 29) I always had short term memory difficultie and "short attention span". She has been prescribe a cholinesterase inhibitor (sorry, I don't have the name with me right now.) wich she feel have amplified her emotional distress. She asked the specialist and her family Doc. to stop this medication and naturally they refuse. I work in agriculture so i am sensibilize to cholinesterase inhibitor as a major problem in pesticide. Causing in long term memory loss. I know that there is something i don't understand here and I want to know what it is. Is it that important that she took this substance consideriing the diagnostics is far from 100% proof at the moment?



    P.S. Please excuse me for the english living in a french contrie it's my second language.

by HFHS MD-JM, Mar 24, 2000 12:00AM
Mario,



     The cholinesterase inhibitors, Aricept and Cognex, act ot increase the availability of acetylcholine in the brain.  This has been shown to improve cognitive function in early to moderate Alzheimers dementia.  The medication is generally well tolerated outside of some gastrointestinal distress.  It is not essential but may be helpful.  I suggest that you discuss this further with your mothers physician.  Keep in mind that emotional distress(ie depression and anxiety) is not uncommon in dementia.  I hope this was helpful.



Sincerely,



HFHS MD-JM



Keywords:  Alzheimers dementia, cholinesterase inhibitors
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