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Neurology (Expert Forum)
central pontine myelinolysis
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central pontine myelinolysis
by Ottilie, Mar 04, 2000 12:00AM
Would like to know if any research is being done on this disease on the brain stem (pons). I have it plus it has caused down beat nystagmus which prevents me from driving. The psychological impact is terrible. I also would like to find someone with this disease. So far I have not.
Doctor's Answer
by CCF Neuro[P] MD, RPS, Mar 04, 2000 12:00AM
Dear Ottilie:
Central pontine myelinosis is usually results from changes in the osmolarity (electrolyte and protein concentration) in the brain versus the blood stream. The abnormal difference between the two causes the myelin surrounding the nerve processes to become unraveled. This inturn causes dysfunction of the nerves in this area. This is not a disease, but the result from an abnormality.
Pontine problems can also arise from stroke in the pons. This will give similar symptoms (although much more focal, such as only downbeat mystagmus). If the stroke is large enough, it can cause complete loss of most movement below the eyes.
So, problems in the pons are usually the result of something.
Sincerely,
CCF Neuro MD
Central pontine myelinosis is usually results from changes in the osmolarity (electrolyte and protein concentration) in the brain versus the blood stream. The abnormal difference between the two causes the myelin surrounding the nerve processes to become unraveled. This inturn causes dysfunction of the nerves in this area. This is not a disease, but the result from an abnormality.
Pontine problems can also arise from stroke in the pons. This will give similar symptoms (although much more focal, such as only downbeat mystagmus). If the stroke is large enough, it can cause complete loss of most movement below the eyes.
So, problems in the pons are usually the result of something.
Sincerely,
CCF Neuro MD
Thank you
No, there is no type of surgery to help this condition.
CCF Neuro MD
No, currently there is no know substance to help remyelinate axons. Sorry that there isn't.
CCF Neuro MD