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Pregnancy  (Expert Forum)
 | 
HCG
Answered by
Keith Downing, MD - Obstetrics, Gynecology
MA
This forum is for questions and support regarding pregnancy issues such as: Alcohol/Drugs, Bleeding, Caesarean Section, Childbirth, Diabetes, Depression, Fetal Monitoring, Genetic Testing, Hormonal Changes, Labor, Lamaze, Morning Sickness, Nutrition, Parenting, Prenatal Care, Weight gain.

HCG

by alwayshope, Sep 26, 2007 09:27AM
I am concerned about my HCG levels. I have been trying to have a child for 8 years and got pregnant naturally. Here’s my numbers 13 DPO hcg-48 progestoerone-32, 15 DPO hcg-103 progesterone 32, 17 DPO hcg-183 prog. 27, and finally 20 DPO 392 prog. 22.

I am nervous as my doubling time is getting longer and progesterone is lowering.

I am not taking any progesterone

by Keith Downing, MD, Oct 01, 2007 10:07AM
Hello,

That is correct, studies in viable intrauterine pregnancies have reported the following changes in serum hCG:

-The mean doubling time for the hormone ranges from 1.4 to 2.1 days in early pregnancy (hence the repeating ~ every 48hrs until a diagnosis made).

-In 85 percent of viable intrauterine pregnancies the hCG concentration rises by at least 66 percent every 48 hours during the first 40 days of pregnancy; only 15 percent of viable pregnancies have a rate of rise less than this threshold.

-The slowest recorded rise over 48 hours associated with a viable intrauterine pregnancy was 53 percent.

Based upon what you report, your hCG seems to be rising okay.  Given this is a spontaneous pregnancy it is unclear if supplemental progesterone will be helpful.  In my patients I don't continue to check Progesterone levels in these circumstances as they are not any more helpful than following the hCG.

Best regards,

Dr. Downing
Member Comments (2)

by fuzybunnyslippers, Sep 26, 2007 10:42PM
I believe most doctors want your hcg to rise 66% - the "doubling" is a myth.  At some point in time, I believe your hcg levels off a bit more.

I would call your doctor and inquire about progesterone.  My doctor had me on prometrium 3xday until the 10th week.

Good luck.
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