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Pregnancy (Expert Forum)
HCG More than Doubling in 48 hrs but Progesterone Dropping!
Answered by
Keith Downing, MD - Obstetrics, Gynecology
MA
This forum is for questions and support regarding pregnancy issues such as: Alcohol/Drugs, Bleeding, Caesarean Section, Childbirth, Diabetes, Depression, Fetal Monitoring, Genetic Testing, Hormonal Changes, Labor, Lamaze, Morning Sickness, Nutrition, Parenting, Prenatal Care, Weight gain.
HCG More than Doubling in 48 hrs but Progesterone Dropping!
by lararobin, Oct 13, 2007 10:09AM
I am 4 wks and 6 days pregnant. Menstrual cycle began 9/8/07. I ovulated on CD 17. My prog at 8 DPO was 22.4. My HCG at 11 DPO was 53 and Prog was 20.1. My HCG at 14 DPO (Mon 10/8) was 299 didn't run prog. My HCG at 17 DPO was 1451 and Prog was 13.7. My OB said she is encouraged by my HCG levels more than doubling and is not too worried about my progesterone b/c the labs can have a pretty good margin of error. She said she is going to prescribe prog suppositories (200mg at night once a day) to ease my worries. I had a chemical pregnancy last month and I have been very worried about this pregnancy. Please give me your thoughts on my progesterone levels and your experiences with the suppository success rates. Thanks!
Doctor's Answer
by Keith Downing, MD, Oct 14, 2007 03:07PM
, Oct 14, 2007 03:07PM
Hello,
There is no known harm in using progesterone supplementation in the setting you describe, however, there is no good evidence, in a spontaneously conceived pregnancy, supplemental progesterone decreases the risk of a miscarriage.
With respect to the progesterone levels, the fact they are dropping is undoubtedly concerning. I don't measure serial progesterone levels in the setting you describe, as it would not influence my management. Your subsequent ultrasound and repeat hCG level should be quite informative regarding the possible early success of your pregnancy.
Stay encouraged,
Dr. Downing
There is no known harm in using progesterone supplementation in the setting you describe, however, there is no good evidence, in a spontaneously conceived pregnancy, supplemental progesterone decreases the risk of a miscarriage.
With respect to the progesterone levels, the fact they are dropping is undoubtedly concerning. I don't measure serial progesterone levels in the setting you describe, as it would not influence my management. Your subsequent ultrasound and repeat hCG level should be quite informative regarding the possible early success of your pregnancy.
Stay encouraged,
Dr. Downing
Dr. Downing,
I'm so confused right now as to what is happening with me. I had a m/c last month at five weeks. I had one before too in June but that was little earlier than 5 weeks.
Now this month I'm about 8 days late with my period. I had some spotting (pinkish sometimes red lining, but only on the tissue) for about two and a half days. This happened a day after my period was due. Usually my period is a lot heavier and longer.
My cycle has always been very regular, about 28 days. This spotting was not like my period at all.
Taken one blood test and about 4 urine tests - all negative. I don't know whats happening with me!!!
My Dr. thinks that I'm not pregnant and said to wait for a week for the period-if it doesn't come I can schedule an appointment for examination. I scheduled an appointment for monday. I have bad cramps in lower abdomen and lower back, I had them last month (when i was pregnant) as well as with my son. I'm only 22, been trying since 8 months now...please advise!!!!
Sabreen