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I'm sorry your daughter has been told she needs antibiotics for the rest of her life. Osteomyelitis is a bacterial infection of the bone and often requires very long term intraveneous antibiotics. Unfortunately, it's a possible consequence of using intravenous drugs, as is Hep C. There's not much you can do for her with respect to these diseases.
For your family member who's on methadone, it's a long acting narcotic pain reliever. They can't drink alcohol, that would certainly make them sick. Alcohol is a depressant and also causes early wakening disturbing sleep which causes tiredness affecting one's behavior.
Go take a vacation!