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This forum is for questions about medical issues and research aspects of Hepatitis C such as, questions about being newly diagnosed, questions about current treatments, information and participation in discussions about research studies and clinical trials related to Hepatitis. If you would like to communicate with other people who have been touched by Hepatitis, please visit our new Hepatitis Social/Living with Hepatitis forum
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Another New Drug in Trial

by Forseegood, Nov 06, 2007 02:51AM
Tags: antiviral
Dutch biotechnology firm OctoPlus said on Tuesday European safety and efficacy Phase IIa studies have shown an antiviral effect for its chronic hepatitis C drug Locteron.

"A statistically significant dose response was observed in the study," the company said in a statement, adding that the drug was tolerated at all doses.

The company, which has four other products in pre-clinical and clinical development, said approximately 90 percent of adverse events were rated as mild.

OctoPlus is co-developing Locteron with its partner Biolex Therapeutics, which plans to commence a European safety and efficacy Phase IIb trial of the drug in mid-2008.

With Locteron, OctoPlus is aiming to develop a treatment for patients with chronic hepatitis C, with fewer side effects and a more convenient dosing schedule compared with current therapies.
Member Comments (4)

by GrandmaA, Nov 06, 2007 12:13PM
To: Forseegood
That's very interesting. Gives the newbies hope.

by sunspot, Nov 06, 2007 02:09PM
To: Forseegood
Thanks for posting about a new Hep-C drug in the pipeline. It gives one hope that this nasty virus can be eliminated in the near future.
I have to give a chuckle about “a more convenient dosing schedule”. That was on the bottom of the complaint list as far as a “cure” was concerned when I treated.

by Forseegood, Nov 06, 2007 02:13PM
To: Sunspot
so good to see you! hope youre doing well....yeah, they seem to be throwing more firepower toward this dang little bug....so many new things happening....

by charm27, Nov 06, 2007 02:32PM
To: Forseegood
Thanks alot for posting that, It is interesting......and eventually something has got to give. :}






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