Member Comments are provided by individuals and reflect their personal opinions only. Under NO circumstances should you act on any advice or opinion posted in this forum. ALWAYS check with your personal physician before taking any action regarding your health! MedHelp International and our partners, sponsors and affiliates have no obligation to monitor any comments posted on this site, or the content and/or accuracy of such exchanges. MedHelp International does not endorse the views of any user.
Genetics (Expert Forum)
HLA - B27 Allele
Answered by
Lisa Kessler, MS, CGC - Hereditary Disorders, hemochromatosis, Patient Outreach
DNA Direct
This forum is for questions and support regarding Genetics.
This forum is for questions and support regarding a person’s predisposition to a variety of medical conditions such as Alzheimer’s Disease, Blood-clotting Disorders, Breast Cancer, Cystic Fibrosis, Diabetes, Marfan Syndrome, Ehlers-Danlos Syndrome, etc.
HLA - B27 Allele
by Kamaljeet, Nov 13, 2007 05:30AM
Hello Doc,
i had joint pain(water on the knees, as doc told me) from last 4 weeks, and my treatement goes with Ortho Specialist. i got my DNA report today and it mentioned that
HLA-B27 Allele Present(Positive)
Doc told me it should be in Negative, so, can you please tell me what i do and it is curable. I am 24, and worried about it. Please do REPLY!!
Thanks,
Kamal
i had joint pain(water on the knees, as doc told me) from last 4 weeks, and my treatement goes with Ortho Specialist. i got my DNA report today and it mentioned that
HLA-B27 Allele Present(Positive)
Doc told me it should be in Negative, so, can you please tell me what i do and it is curable. I am 24, and worried about it. Please do REPLY!!
Thanks,
Kamal
Doctor's Answer
by Lisa Kessler, MS, CGC, Nov 16, 2007 02:34PM
, Nov 16, 2007 02:34PM
To: Kamal
I hope that this information is helpful to you. Having one copy of the HLA – B27 allele causes an increased risk to develop ankylosing spondylitis, a form of chronic inflammation of the spine and of particular joints in the spine. It can also cause problems with the eyes called Iritis. In addition to HLA-B27, there are most likely other genetic and environmental factors associated with this condition. The chance of developing ankylosing spondylitis with one positive HLA B27 allele is 43%. You should talk with your doctor about the results of the test. It is important to keep in mind that most people with a copy of the HLA-B27 allele never go on to develop any symptoms of ankylosing spondylitis.
Member Comments (2)
by Kamaljeet, Nov 18, 2007 11:41AM
Thanx for the informartion. really appriciable. my treatment going with Ortho Specialist (surgen too), and i am getting releife with his medicines. do i need to consult Reumathologis or continue wit h my Ortho Doc?
