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Genetics  (Expert Forum)
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47,xyy
Answered by
Lisa Kessler, MS, CGC - Hereditary Disorders, hemochromatosis, Patient Outreach
DNA Direct
This forum is for questions and support regarding Genetics. This forum is for questions and support regarding a person’s predisposition to a variety of medical conditions such as Alzheimer’s Disease, Blood-clotting Disorders, Breast Cancer, Cystic Fibrosis, Diabetes, Marfan Syndrome, Ehlers-Danlos Syndrome, etc.

47,xyy

by jd101, Jan 05, 2008 01:27AM
we just found out through testing that our unborn child has 47,xyy.  We are really struggling to get straight answers on what this means for him and expectations for his life.  Can you suggest any good reliable contacts or sources of information to help us understand the situation?

by Lisa Kessler, MS, CGC, Jan 07, 2008 09:50AM
It can be very difficult when something unexpected comes up during a pregnancy.  Most often, 47, XYY does not cause unusual physical features or health problems.  Sometimes men can be taller, have an increased risk for learning disabilities, and can have speech delays.  1 in 1000 boys have 47, XYY.  

Typically we have 46 chromosomes in all of our cells.  Our chromosomes come in pairs, and we inherit one member of each pair from our mother, and one from our father.  Boys with 47, XYY have an extra copy of the Y chromosome.   It is generally not inherited, but occurs randomly when sperm cells were being formed.  In order to learn more about this condition, it may help you to talk with a genetic counselor.  You can locate a genetic counselor near you using the National Society of Genetic Counselor’s website.  I wish you and your family the best.
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