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Fertility / Infertility  (Expert Forum)
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Hysteroscopy/Biopsy Results Questionable
Questions in the Fertility/Infertility forum are answered by doctors affiliated with USF Health. Topics covered include fertility or infertility issues, egg quality, fertility drugs and side effects, fertility tests, genetic testing, in-vitro fertilization (IVF), ovulation, relationship issues, risk factors, sperm count/quality, and surgery.

Hysteroscopy/Biopsy Results Questionable

by paranoidpatty, Apr 25, 2007 12:00AM
I had an office hysteroscopy on CD7, and results said I wasn't ovulating even though my BBT is biphasic & OPKs are positive. My GYN said the biopsy indicated that my uterine lining shows that it is not responding to Progesterone so I'm not Ovulating and I had too much Estrogen.

I researched on my own and found that the biopsy should be done BEFORE AF in the luteal phase and not in the beginning of the cycle like I had. It sounds like the GYN made a mistake and biopsied me before and didnt pay any mind to what day of my cycle it was, only what day was available for the procedure. In other words, how can you test if the uterine lining is responding to Progesterone when the hormone is not even produced until ovulation? Also, since Estrogen is dominant in the beginning of the cycle, how can that be a problem? I honestly think they made a mistake!! What type of uterine biopsy could provide evidence of anovulation BEFOREHAND???? Maybe the lab made a mistake on the cycle date? Please let me know if you could detect anovulation by a uterine biopsy on CD7.  Also, should I be searching for a new doc?

Thanks in advance!!

by Forum-M.D.-SP, Apr 25, 2007 12:00AM
You are correct - a biopsy on day 7 will not be able to tell if you are ovulating. In my opinion, your BBTs and OPKs confirm that you are ovulatory.
Member Comments (2)

by paranoidpatty, Apr 25, 2007 12:00AM
A few notes, I'm 38, two children and was diagnosed with low Progesterone (7.1) a few months back.  Also, I think the same biopsy report noted disordered ovulation/uterus???
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