chronic diahrea no diagnosis

[jea44]

My wife has had chronic diahrea since october of last year. Paid a visit to the emergency room only to find nothing. Had blood in stool and a positive fecal ocult test after visiting the Family doctor.
She ordered some blood work and scheduled a colonoscopy. The blood work came back negative for bacteria and parasites. The colonoscopy results was mild chronic inflamation/hemmorage, the biopsy did not show colitis or crohns in the large bowel. Started a round of tests to include a lower abdomen ultrasound, nothing found. did a Small Bowel Ultrasound with barium and it showed an abnormal area in the small bowel. Blood work was also done and found anemia and inflamation. The doctor ordered a specific test for IBD and it showed negative for Crohns or UC. The diahrea has not subsided up to 5  or 6 times a day. Mucous, blood (but not all the time). watery.
Found Galstones during the Ultrasound as well.
Does anyone have any suggestions as to what this might be?

[CalGal]

If the specific test was an antibody test for either Crohn's or UC, they're not always 100% perfect. Based on what you're saying was seen, it would suggest that your wife may have either Crohn's, or possibly as an 'out-lier' microscopic colitis with gluten/celiac involvement. I know that's vague, but the first thought would be Crohn's because of the small intestinal involvement. And your wife may not be producing the antibodies yet that would show up on the other test.

Were any changes found during the colonoscopy at the terminal ileum? You mention some mild chronic inflammation in the colonoscopy, but didn't mention where that was seen.

What specifically did the biopsy show?

Based on the findings, is your doc going to treat your wife as if she is dealing with a form of IBD? And is there any history of IBDs of any form in your wife's family?

[jea44]

For the Upper GI endoscopy it showed gastric musocal abnormality characterized by erythema, this was biopsied, showed normal examined dueodenum, which was biopsied as well. For the colonoscopy the impression was congested mucosa from rectum to spenic flexure this was biopsied.
The colonoscopy showed the left colon biopsy showing non-specific mild acute and chronic inflammation and hemorrhage with no evidence of microscopic or collagenous colitis. The same for the right colon biopsy. The rectum biopsies showing the same.
For the small bowel biopsy showing preserved villous architecture with non-specific mild acute and chronic inflammation and no evidence of sprue. Gastric biopsy showing mild acute and chronic inflammation with no evidence of H. Pylori Organisms.
For the Fluoroscpoic small bowel study. Conclusion Fold thickening in the distal ileum approximately 10-20 cm proximal to the terminal ileum. This is consistent with focal submucosal edema, hemorrhage or infiltration. Says the terminal ileum is with abnormality as is the rest of the small bowel. no mass lesion seen.
The only results I am waiting on are the video capsule endoscopy.

[CalGal]

Have they considred the possibility of vasculitis? I know it may be a long shot, but with the extensive nature of the hemorrhagic features.................?

[jea44]

I'll bring it up. we've got a follow up visit this month, should have the video capsule endoscopy by that time as well. Thanks for your help.

[Kiki50plus]

To Jea
Have you heard of Haab Syndrome? I believe this is what I have and the treatment
is working. Good Luck
Kiki

[jea44]

Kiki, nope, tried to google this did not find anything. Is it know as anything else?

[boron]

Are there any extra-intestinal symptoms, like skin rash, eye involvment, arthritis...? Also, how old is she?

You've said:
congested colonic mucosa
inflammation in terminal ileum
gastric mucosa erythema
inflammation, showed by