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Fertility / Infertility (Expert Forum)
Clomid Success one cycle and not the next?
Answered by
Shayne Plosker, MD - fertility, infertility
USF Health
Questions in the Fertility/Infertility forum are answered by doctors affiliated with USF Health. Topics covered include fertility or infertility issues, egg quality, fertility drugs and side effects, fertility tests, genetic testing, in-vitro fertilization (IVF), ovulation, relationship issues, risk factors, sperm count/quality, and surgery.
Clomid Success one cycle and not the next?
by analynn79, Feb 18, 2008 12:51PM
I have PCOS. Not really traditional because all I have is bad acne and annovulatory cycles. I have been on Clomid for 4 cycles now. We started out at 50mg, no ovulation. We went to 100mgs, no ovulation. We went to 150mgs and BINGO! Ovulation. (along with many other alternative things I do - as well as being treated for a vitamin deficiency (it's called Pyrolurria)) So last cycle I o'd on cd 16. This cycle I decided to stay with the clomid since it obviously worked last cycle. I am on CD 19 this cycle and so far nothing. No EWCM ( Inver have had any good EWCM). No temp shift nothing. The only good thing is that my cervical position is high and open. My question is: is this possible that Clomid worked the one cycle and not the next? Or am I getting to anxious and need to wait to see if if I really do ovulate? Can It happen later than the first cycle?
Doctor's Answer
by Shayne Plosker, MD, Feb 28, 2008 11:54PM
, Feb 28, 2008 11:54PM
To: analynn79
Dear analynn79 - it is not that unusual for clomid to work one month and then not the next. There are several ways to determine if you are ovulating. The most accurate is to get a blood test for a hormone called progesterone, which is elevated in the blood after ovulation. A progesterone drawn on days 21,22, or 23, if elevated, shows that you ovulated on clomid this month. If it is low, then you would probably want to bring on a period with provera, then try clomid at the 200 mg dose. Down the road, if clomid doesn't work, either fertility injection drugs or a pill called letrozole can be sonsidered.
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I'm starting the Clomid this month and am really exctied but also apprehensive. I don't want to get my hopes up. How did you know that you had ovulated? I am annovulatory also....and I never know when I ovulate or when I don't.....any response would be helpful. Sorry I can't help you. :o(